Sulforaphane promotes white matter plasticity and improves long-term neurological outcomes after ischemic stroke via the Nrf2 pathway

CONCLUSION: Our results support that Nrf2 is critical for Sfn-afforded neuroprotection after ischemic stroke. Thus, targeting Nrf2 may be a promising strategy for the treatment of PSCI.PMID:36244590 | DOI:10.1016/j.freeradbiomed.2022.10.001

Source: Free Radical Biology and Medicine - October 16, 2022 Category: Biology Authors: Qianqian Li George Fadoul Milos Ikonomovic Tuo Yang Feng Zhang Source Type: research