Epicentral Disruption of Structural Connectivity in Alzheimer's Disease.

CONCLUSION: Our results favor an epicentral disruption of structural connectivity in aMCI and AD around entorhinal and hippocampal regions, consistent with the transneuronal spread hypothesis.
PMID: 25899584 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - April 21, 2015 Category: Neuroscience Authors: Mallio CA, Schmidt R, de Reus MA, Vernieri F, Quintiliani L, Curcio G, Beomonte Zobel B, Quattrocchi CC, van den Heuvel MP Tags: CNS Neurosci Ther Source Type: research