Prefrontal Cortex Volume Mediates the Relationship Between Lifetime Chronic Stressor Exposure and Cognition in People Living With and Without HIV

Conclusions These results highlight the critical role of the PFC in the maintenance of processing speed abilities and its vulnerability to cumulative stressor exposure. Specifically, the negative impact of lifetime chronic stressor exposure on cognition—particularly functions reliant on frontal lobe integrity—may be partly driven by smaller volumes in the PFC.
Source: Psychosomatic Medicine - Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research