Overactivation of NR2B‐containing NMDA receptors through entorhinal‐hippocampal connection initiates accumulation of hyperphosphorylated tau in rat hippocampus after transient middle cerebral artery occlusion (MCAO)

This study indicates that early inhibition of NR2B‐containing NMDARs may represent a potential strategy to prevent or delay the occurrence of post‐stroke dementia. This article is protected by copyright. All rights reserved.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fjnc.13134

Source: Journal of Neurochemistry - April 22, 2015 Category: Neuroscience Authors: Cheng‐Shi Xu, An‐Chun Liu, Juan Chen, Zhi‐Yong Pan, Qi Wan, Zhi‐Qiang Li, Ze‐Fen Wang Tags: Original Article Source Type: research