Housebreaking Plasmodium parasites leave their fingerprints at the door

Trends Parasitol. 2022 Sep 23:S1471-4922(22)00209-4. doi: 10.1016/j.pt.2022.09.005. Online ahead of print.ABSTRACTProtective antibodies against Plasmodium falciparum merozoite antigens, including EBA-175, can inhibit erythrocyte invasion. New data from Musasia et al. indicate that these antibodies can also trigger antibody-dependent phagocytosis of ring-infected and uninfected erythrocytes and that this correlates with protection from malaria. This provides a new pathway for vaccine design.PMID:36163104 | DOI:10.1016/j.pt.2022.09.005
Source: Trends in Parasitology - Category: Parasitology Authors: Source Type: research