Genetic determinants associated with response to clozapine in schizophrenia: an umbrella review

Conclusions Conclusive evidence for associations between genetic variants and clozapine response is still lacking. Hypothesis-generating genetic studies in large, well-characterized study populations are urgently needed to obtain more consistent and clinically informative results. Future studies may also include multi-omics approaches to identify novel genetic determinants associated with clozapine response.
Source: Psychiatric Genetics - Category: Genetics & Stem Cells Tags: Review Article Source Type: research