Selective decrease in alpha < sub > 1 < /sub > -antitrypsin levels in diabetic retinopathy: Could the levels of it be playing a role in the pathophysiology of diabetic retinopathy?

CONCLUSIONS: Homeostasis of NE, α1-AT and α2-MG is disrupted in T2DM, DN and DR. Strikingly reduced levels of α1-AT observed in DR are indicative of its possible role in the pathophysiology of retinopathy and emphasizes α1-AT as a plausible therapeutic target.PMID:36124492 | DOI:10.4103/ijmr.IJMR_1293_19
Source: The Indian Journal of Medical Research - Category: Biomedical Science Authors: Source Type: research