Calcitriol potentially alters HeLa cell viability via inhibition of autophagy

Conclusion: We suggest that Calcitriol may shut down mitochondrial homeostasis in HeLa cells by inducing the PI3K-AKT-mTOR pathway and inhibiting autophagy, which leads to cell death.

Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Iwan Setiawan Ronny Lesmana Hanna Goenawan Dodi Suardi Vesara Ardhe Gatera Rizky Abdulah Raden Tina Dewi Judistiani Unang Supratman Budi Setiabudiawan Source Type: research