Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?

Conclusions TERT mRNA seems to be focally expressed and localised exclusively to the nucleus in TERT promoter mutated follicular thyroid tumours, possibly reflecting a true biological and unorthodox phenomenon worthy of further investigations.

http://jcp.bmj.com/cgi/content/short/75/10/658?rss=1

Source: Journal of Clinical Pathology - September 19, 2022 Category: Pathology Authors: Hellgren, L. S., Olsson, A., Kaufeldt, A., Paulsson, J. O., Hysek, M., Stenman, A., Zedenius, J., Larsson, C., Höög, A., Juhlin, C. C. Tags: Open access Original research Source Type: research