Atrial fibrillation, thromboembolic risk, and anticoagulation in cardiac amyloidosis: A review

Cardiac amyloidosis results from deposition of abnormal proteins in the heart called amyloid. This protein deposition leads to changes in the heart structure that ultimately predispose to rhythm disturbances, notably atrial fibrillation. The toxic effect of these proteins on the heart as well as resulting structural abnormalities often cause blood clots to form inside the heart, which can lead to stroke. Simultaneously, amyloid proteins can also increase risk of bleeding. Blood thinners are often needed in these patients to prevent stroke.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Tags: Review Article Source Type: research