PARP targeted Auger emitter therapy with [125I]PARPi-01 for triple-negative breast cancer

ConclusionConsidering the radio-cytotoxic effect in the tumour tissue and a delay on tumour doubling time, [125I]PARPi-01 presents a potential radiotherapeutics for treatment of TNBC. Improvements to overcome the suboptimal pharmacokinetics are necessary for its potential clinical application.
Source: EJNMMI Research - Category: Radiology Source Type: research