Clinical and Genetic Features of Multiplex Families with Multiple System Atrophy and Parkinson ’s Disease

This study further emphasizes the occurrence of MSA and PD in first-degree relatives, raising the possibility that a common genetic basis underlies MSA and PD. Even though variants ofCOQ2 andGBA were identified in some patients in multiplex families with MSA and PD, it is necessary to further explore as yet unidentified genetic risk factors shared by MSA and PD.
Source: The Cerebellum - Category: Neurology Source Type: research