Arctium lappa leaves based on network pharmacology and experimental validation attenuate atherosclerosis by targeting the AMPK-mediated PPARG/LXR α pathway

In conclusion, A. lappa leaves attenuated AS-induced cholesterol accumulation by targeting the AMPK-mediated PPARG/LXRα pathway and promoting cholesterol efflux.PMID:36076592 | DOI:10.1016/j.biopha.2022.113503

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 9, 2022 Category: Drugs & Pharmacology Authors: Mengmeng Wang Bingdi Cui Man Gong Qiuyan Liu Xingxu Zhuo Jiangnan Lv Lianhe Yang Xiaoqian Liu Zhimin Wang Liping Dai Source Type: research