Synergistic effect of serotonin 1A and serotonin 1B/D receptor agonists in the treatment of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats

CONCLUSIONS: The strong anti-dyskinetic effect found with combined 5-HT1A and 5-HT1B/D agonism renders buspirone and zolmitriptan together a meaningful treatment for LID in PD.PMID:35988699 | DOI:10.1016/j.expneurol.2022.114209

Source: Experimental Neurology - August 21, 2022 Category: Neurology Authors: Mikael Thomsen Anca Stoica Kenneth Vielsted Christensen Tue Fryland Jens D Mikkelsen John Bondo Hansen Source Type: research