Ethnic and National Differences in Congenital Adrenal Hyperplasia Incidence: A Systematic Review and Meta-analysis

Conclusions: This study highlights the at-risk population for CAH and regions that need monitoring for CAH. The highest CAH incidence could be attributed to higher consanguinity, less genetic diversity, or ot her genetic causes since CAH is an inherited genetic disorder. Cultural practices in some places regarding consanguineous unions or geographic isolation may directly affect the incidence. Newborn screening for CAH may be unavailable in many developing countries, thereby affecting the actual CAH inci dence. Therefore, healthcare workers should be trained to recognize CAH at an early stage to reduce its complications and mortality.
Source: Hormone Research in Paediatrics - Category: Endocrinology Source Type: research