Improved SARS-CoV-2 sequencing surveillance allows the identification of new variants and signatures in infected patients

ConclusionIn conclusion, we have successfully generated an optimized and cost-effective strategy to monitor SARS-CoV-2 genetic variability, without the need of automation. Thus, our approach is suitable for any lab with a benchtop sequencer and a limited budget, allowing an integrated genomic surveillance on premises. Finally, we have also identified a gene expression signature defining SARS-CoV-2 infection in real-world patients ’ upper respiratory ways.
Source: Genome Medicine - Category: Genetics & Stem Cells Source Type: research