CD40/TRAF1 decreases synovial cell apoptosis in patients with rheumatoid arthritis through JNK/NF- κB pathway

ConclusionsHigh levels of TRAF1 in RA synovium play an important role in the synovial hyperplasia of RA by suppressing apoptosis through activating JNK/NF-kB-dependent signaling pathways in response to the engagement of CD40.
Source: Journal of Bone and Mineral Metabolism - Category: Orthopaedics Source Type: research