Multi-omics analyses of MEN1 missense mutations identify disruption of menin –MLL and menin–JunD interactions as critical requirements for molecular pathogenicity
Loss-of-function mutations of the multiple endocrine neoplasia type 1 (MEN1) gene are causal to the MEN1 tumor syndrome, but they are also commonly found in sporadic pancreatic neuroendocrine tumors and other typ...
Source: Epigenetics and Chromatin - Category: Genetics & Stem Cells Authors: Koen M. A. Dreijerink, Ezgi Ozyerli-Goknar, Stefanie Koidl, Ewoud J. van der Lelij, Priscilla van den Heuvel, Jeffrey J. Kooijman, Martin L. Biniossek, Kees W. Rodenburg, Sheikh Nizamuddin and H. T. Marc Timmers Tags: Research Source Type: research
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