TIMP-1 expression in coronary thrombi associate with myocardial injury in ST-elevation myocardial infarction patients

Conclusion MMP-2, MMP-9, TIMP-1, TIMP-2 and EMMPRIN were highly expressed in human coronary thrombi. The correlation between troponin T and the expression of TIMP-1 both in thrombi and in leukocytes at time of PCI indicates that TIMP-1 plays a role in myocardial damage early post-MI.
Source: Coronary Artery Disease - Category: Cardiology Tags: Original Research Source Type: research