A cross-sectional study on thrombopoietin levels in immune thrombocytopenia and its correlation with platelet count, megakaryocytes, and treatment response
CONCLUSION: Quantitative alterations in TPO are in a way regulated by qualitative efficacy of megakaryocytes rather than platelet or megakaryocyte count. Nonresponders with markedly increased TPO levels (due to qualitative megakaryocyte injury) are less likely to respond to TPO receptor agonist.
Source: Asian Journal of Transfusion Science - Category: Hematology Authors: Gurleen Oberoi Mili Jain Shankar Madhav Natu Rashmi Kushwaha Anil Kumar Tripathi Ashutosh Kumar Source Type: research