Sex differences in cytokine profiles during suppressive antiretroviral therapy

Conclusion: The observed sex-based differences in cytokines might contribute to higher immune activation in women compared with men despite suppressive therapy. Increased levels of IL-7 in women suggest that homeostatic proliferation may have a differential contribution to HIV reservoir maintenance in female and male individuals. Our study emphasizes the importance of sex-specific studies of viral pathogenesis.
Source: AIDS - Category: Infectious Diseases Tags: BASIC SCIENCE Source Type: research