17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson ’s disease are associated with LRRC37A/2 expression in astrocytes

Parkinson ’s disease (PD) is genetically associated with the H1 haplotype of the MAPT 17q.21.31 locus, although the causal gene and variants underlying this association have not been identified.

Source: Molecular Neurodegeneration - July 15, 2022 Category: Neurology Authors: Kathryn R. Bowles, Derian A. Pugh, Yiyuan Liu, Tulsi Patel, Alan E. Renton, Sara Bandres-Ciga, Ziv Gan-Or, Peter Heutink, Ari Siitonen, Sarah Bertelsen, Jonathan D. Cherry, Celeste M. Karch, Steven J. Frucht, Brian H. Kopell, Inga Peter, Y. J. Park & hell Tags: Research article Source Type: research