Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy

ConclusionsCollectively, our data suggest that tau is likely acting downstream of αS pathology to affect neuronal homeostasis and survival. This work further supports the investigation of tau in α-synucleinopathies to identify novel disease-modifying therapeutic strategies.
Source: Translational Neurodegeneration - Category: Neurology Source Type: research