The effects of sigma (σ1) receptor‐selective ligands on muscarinic receptor antagonist‐induced cognitive deficits in mice

Conclusions and ImplicationsThe σ1 receptor‐selective compound LS‐1–137 may represent a novel candidate cognitive enhancer for the treatment of muscarinic receptor‐dependent cognitive deficits.

Source: British Journal of Pharmacology - April 10, 2015 Category: Drugs & Pharmacology Authors: Maninder Malik, Claudia Rangel‐Barajas, Nathalie Sumien, Chang Su, Meharvan Singh, Zhenglan Chen, Ren‐Qi Huang, Johann Meunier, Tangui Maurice, Robert H Mach, Robert R Luedtke Tags: RESEARCH PAPER Source Type: research