Impact of informational feedback to clinicians on antibiotic-prescribing rates in a tertiary care hospital in Delhi
Conclusions: In view of unfavourable results of passive intervention in the above study, active intervention may be more effective.
ConclusionsResistant MTB isolates in Algeria harbour resistance genotypes similar to other countries, but some rare patterns may result from selection and transmission processes inherent to the country.
ConclusionCirculating MDR A. baumannii exhibit genetic heterogeneity with variations in the structure and content of genomic A. baumannii resistance islands and encode multiple putative ARGs. This report represents the first clonal subtype information and genomic characterization of MDR A. baumannii in the country of Georgia and may inform future epidemiological investigations.
The World Health Organization Supranational TB Reference Laboratory Network (SRLN) has served as the backbone for TB drug-resistance surveillance and diagnosis since 1994 and remains a key WHO programme for antimicrobial resistance (AMR) surveillance at the global level. SRLN is a great technical resource for proficiency testing to ensure accuracy of drug-susceptibility testing, scale-up, capacity development in countries and provides unique support to the reliable detection of drug resistance. Technical assistance from individual SRLs has been supported by a variety of mechanisms but funding for the SRLN has become increasingly challenging.
ConclusionESBL/AmpC-E. coli colonized the gut of travelers to Vietnam with a CTX-resistant E. coli (>107 CFU/g feces), and the colonization lasted 14 weeks.
ConclusionsThe findings of this study will contribute to the design of appropriate interventions, based on local evidence, for the establishment of antimicrobial stewardship programs in a country characterized by excessive use of antimicrobials and high resistance rates.
Publication date: Available online 11 November 2019Source: Journal of Global Antimicrobial ResistanceAuthor(s): Jayalaxmi Wangkheimayum, Trisha Datta Majumder, Yasmin Begam Tapadar, Bhaskar Jyoti Das, Deepjyoti Paul, Debadatta Dhar, Atanu Chakravarty, Amitabha Bhattacharjee
The quorum sensing (QS) system controls bacterial biofilm formation, which is highly related to the virulence and resistance of pathogens. In the present study, the effect of two traditional Chinese medicine (TCM) monomers, berberine and matrine, on biofilm formation and QS-related gene expression of antimicrobial-resistant (AMR) Escherichia coli strains was investigated by laser scanning confocal microscopy (LSCM) observation and real-time PCR. The results indicated a roughly positive relationship between biofilm formation ability and antimicrobial resistance. LSCM observation showed that berberine and matrine inhibited b...
(Council of Canadian Academies) CCA expert panel study provides new data on potential impact of antimicrobial resistance in Canada.
A new microneedle biosensor that noninvasively monitors penicillin levels in the body could help to ensure that each patient gets the right antibiotic dose, potentially improving outcomes while reducing adverse effects and antimicrobial resistance. The device fills the need for more personalized antibiotic prescribing amid increasing recognition that people handle antimicrobials differently based on their individual physiology, comorbidities, and clinical scenarios.
In conclusion, this study provided information on the structural variation of ICEMh1-like elements, refined the ICE insertion site and potential host range, and demonstrated the risk and consequences for AMR following horizontal transfer of ICE into BRD pathogens.