Low plasma insulin-like growth factor-1 associates with increased mortality in chronic kidney disease patients with reduced muscle strength

Chronic kidney disease (CKD) leads to metabolic and nutritional abnormalities including resistance to insulin-like growth factor-1 (IGF-1) action, and reduced muscle mass and strength. Low IGF-1 as well as low handgrip strength (HGS) are independent predictors of increased mortality in CKD patients.

Source: Journal of Renal Nutrition - July 2, 2022 Category: Urology & Nephrology Authors: Zhimin Chen, Erik Nilsson, Bengt Lindholm, Olof Heimb ürger, Peter Barany, Peter Stenvinkel, Abdul Rashid Qureshi, Jianghua Chen Tags: Original Research Source Type: research