Dual-specificity phosphatase 8 (DUSP8) induces drug resistance in breast cancer by regulating MAPK pathways

In conclusion, knockdown of DUSP8 expression in trastuzumab-resistant cells can inhibit cell migration and proliferation, and leads to decreased drug resistance by activating MAPK signaling pathway in trastuzumab-resistant cells.

Source: Journal of Investigative Medicine - June 22, 2022 Category: Research Authors: Zhang, H., Wang, M., Chen, D., Luo, C. Tags: Original research Source Type: research