PARP1 rs1136410 (A/G) polymorphism is associated with early age of onset of gallbladder cancer

Conclusion Our study suggests that the minor allele G of PARP1 rs1136410 (A/G) is a predisposing factor for gallbladder carcinogenesis and is significantly associated with early onset of the disease. Interestingly, the minor allele G is significantly more frequent in the patients with jaundice, lymph node metastasis and gallbladder wall thickness.
Source: European Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Epidemiology Source Type: research