Regulation of brain iron uptake by apo- and holo-transferrin is dependent on sex and delivery protein

ConclusionsThese findings extend our previous work to demonstrate that the regulation of brain iron uptake is influenced by both the mode in which iron is delivered and sex. These findings further emphasize the role of the microvasculature in regulating brain iron uptake and the importance of cues regarding iron status in the extracellular fluid.

Source: Fluids and Barriers of the CNS - June 10, 2022 Category: Neuroscience Source Type: research