Tenofovir diphosphate in dried blood spots predicts future viremia in persons with HIV taking antiretroviral therapy in South Africa
Objectives:
Tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) is used as a biomarker of antiretroviral therapy (ART) adherence. Recent treatment studies have shown that TFV-DP predicts future viremia in persons with HIV (PWH) but there are few data from high-burden settings. We investigated whether TFV-DP in DBS predicts future viral breakthrough in South African PWH.
Design:
Prospective observational cohort.
Methods:
We enrolled 250 adults receiving tenofovir-containing regimens, currently virally suppressed (
Source: AIDS - Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research
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