Novel mechanisms of pain in painful diabetic neuropathy

Nature Reviews Endocrinology, Published online: 08 June 2022; doi:10.1038/s41574-022-00710-6A recent study has generated compelling experimental data on the role of GPR177 and WNT5a in the pathogenesis and treatment of painful diabetic neuropathy (PDN). The clinical value of these translational findings should be interpreted with caution. However, the limited efficacy of current treatments for PDN warrants further clinical studies on these novel pathways.
Source: Nature Reviews Endocrinology - Category: Endocrinology Authors: Source Type: research