Molecules, Vol. 28, Pages 2171: Metal Complexes with Naphthalene-Based Acetic Acids as Ligands: Structure and Biological Activity
somas
Naproxen (6–methoxy–α–methyl–2–naphthaleneacetic acid), 1–naphthylacetic acid, 2–naphthylacetic acid and 1–pyreneacetic acid are derivatives of acetic acid bearing a naphthalene-based ring. In the present review, the coordination compounds of naproxen, 1– or 2–naphthylacetato and 1–pyreneacetato ligands are discussed in regard to their structural features (nature and nuclearity of metal ions and coordination mode of ligands), their spectroscopic an...
Source: Molecules - February 26, 2023 Category: Chemistry Authors: Marialena Lazou Spyros Perontsis George Psomas Tags: Review Source Type: research
Molecules, Vol. 28, Pages 2185: Evaluation of the Defined Bacterial Consortium Efficacy in the Biodegradation of NSAIDs
yńska
Due to the increasing pollution of wastewater with non-steroidal anti-inflammatory drugs, preparations need to be developed to decompose these drugs. This work aimed to develop a bacterial consortium with a defined composition and boundary conditions for the degradation of paracetamol and selected non-steroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, naproxen, and diclofenac. The defined bacterial consortium consisted of Bacillus thuringiensis B1(2015b) and Pseudomonas moorei KB4 strains in a ratio of 1:2. During the tests, it was shown that the bacterial consortium worked in the pH range from 5.5...
Source: Molecules - February 26, 2023 Category: Chemistry Authors: Ariel Marchlewicz Urszula Guzik Katarzyna Hupert-Kocurek Danuta Wojcieszy ńska Tags: Article Source Type: research
Molecules, Vol. 28, Pages 2174: Boron Lewis Acid Catalysis Enables the Direct Cyanation of Benzyl Alcohols by Means of Isonitrile as Cyanide Source
Jian-Jun Feng
The development of an efficient and straightforward method for cyanation of alcohols is of great value. However, the cyanation of alcohols always requires toxic cyanide sources. Herein, an unprecedented synthetic application of an isonitrile as a safer cyanide source in B(C6F5)3-catalyzed direct cyanation of alcohols is reported. With this approach, a wide range of valuable α-aryl nitriles was synthesized in good to excellent yields (up to 98%). The reaction can be scaled up and the practicability of this approach is further manifested in the synthesis of an anti-inflammatory drug, naproxen....
Source: Molecules - February 26, 2023 Category: Chemistry Authors: Tong-Tong Xu Jin-Lan Zhou Guang-Yuan Cong Jiang-Yi-Hui Sheng Shi-Qi Wang Yating Ma Jian-Jun Feng Tags: Article Source Type: research
Efficacy of oral nifedipine, naproxen, or placebo for pain relief during diagnostic hysteroscopy in an office setting: a randomized pilot study.
To compare nifedipine, naproxen, or placebo for pain relief during diagnostic hysteroscopy. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - February 15, 2023 Category: OBGYN Authors: Steffi van Wessel, Julie Rombaut, Astrid Vanhulle, Mark Hans Emanuel, Tjalina Hamerlynck, Steven Weyers Tags: ORIGINAL ARTICLE Source Type: research
Preparation of molecularly imprinted silica particles with amino functionality for chiral separation of ( ±)-naproxen
Chirality. 2023 Feb 7. doi: 10.1002/chir.23541. Online ahead of print.ABSTRACTHerein is the synthesis and effective use of an S-naproxen (S-NP) enantioselective adsorbent material with amino functionality for the enantioseparation of a (±)-NP racemic mixture. To begin, the S-NP enantiomer of (3-aminopropyl)triethoxysilane was used to create an amide derivative (S-NP-Si-NH2 ). In order to incorporate the S-NP enantiomeric species into the cross-linked material, the developed S-NP-Si-NH2 derivative was combined with tetraethoxysilane (TEOS) and subjected base-catalyzed sol-gel condensation polymerization procedure. The S-NP...
Source: Chirality - February 8, 2023 Category: Molecular Biology Authors: Abeer Abdulaziz H Bukhari Source Type: research
