Ezetimibe-Loaded Nanostructured Lipid Carrier for Oral Delivery: Response Surface Methodology; In Vitro Characterization and Assessing the Antihyperlipidemic Effect in Rats
ACS Omega. 2024 Feb 12;9(7):8103-8116. doi: 10.1021/acsomega.3c08428. eCollection 2024 Feb 20.ABSTRACTAmong the independent risk factors for the occurrence of cardiovascular diseases like atherosclerosis is hyperlipidemia. To decrease cardiovascular events and patient mortality, antihyperlipidemia therapy is crucial. Our study aimed to enhance the solubility of the poorly soluble lipid-lowering agent ezetimibe (EZ), a member of class II as per the Biopharmaceutics Classification System (BCS). The drug was formulated as a nanostructured lipid carrier (NLC) employing the ultrasonication technique. A response surface D-optima...
Source: Atherosclerosis - February 26, 2024 Category: Cardiology Authors: Dalia Elkhayat Nevine S Abdelmalak Reham Amer Heba H Awad Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
Risk of Hemorrhagic Stroke among Patients Treated with High-Intensity Statins versus Pitavastatin-Ezetimibe: A Population Based Study
Tohoku J Exp Med. 2024 Feb 22. doi: 10.1620/tjem.2024.J019. Online ahead of print.NO ABSTRACTPMID:38382969 | DOI:10.1620/tjem.2024.J019 (Source: The Tohoku Journal of Experimental Medicine)
Source: The Tohoku Journal of Experimental Medicine - February 21, 2024 Category: Research Authors: Po-Sheng Chen Jia-Ling Lin Hui-Wen Lin Sheng-Hsiang Lin Yi-Heng Li Source Type: research
