Tackling the neurological manifestations in Wilson's disease - currently available treatment options
Expert Rev Neurother. 2023 Jul-Dec;23(12):1249-1259. doi: 10.1080/14737175.2023.2268841. Epub 2023 Dec 15.ABSTRACTINTRODUCTION: Wilson's disease (WD) is a potentially treatable, inherited disorder resulting from impaired copper metabolism. Pathological copper accumulation causes a range of symptoms, most commonly hepatic and a wide spectrum of neurological symptoms including tremor, dystonia, chorea, parkinsonism, dysphagia, dysarthria, gait and posture disturbances. To reduce copper overload, anti-copper drugs are used that improve liver function and neurological symptoms in up to 85% of patients. However, in some WD pati...
Source: Expert Review of Neurotherapeutics - October 16, 2023 Category: Neurology Authors: Tomasz Litwin Petr Dusek Agnieszka Antos Anna Cz Å‚onkowska Jan Bembenek Source Type: research