< em > Huangpu Tongqiao < /em > Capsule improves cognitive impairment in rats with Wilson disease by inhibiting endoplasmic reticulum stress-mediated apoptosis pathway
CONCLUSION: HPTQ Capsule has neuroprotective effects in rat models of WD possibly by inhibiting ERS-mediated apoptosis pathway.PMID:38597435 | DOI:10.12122/j.issn.1673-4254.2024.03.05 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: X Zhang X Wang J Wang N Shao B Cai D Xie Source Type: research

< em > Huangpu Tongqiao < /em > Capsule improves cognitive impairment in rats with Wilson disease by inhibiting endoplasmic reticulum stress-mediated apoptosis pathway
CONCLUSION: HPTQ Capsule has neuroprotective effects in rat models of WD possibly by inhibiting ERS-mediated apoptosis pathway.PMID:38597435 | PMC:PMC11006687 | DOI:10.12122/j.issn.1673-4254.2024.03.05 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: X Zhang X Wang J Wang N Shao B Cai D Xie Source Type: research

< em > Huangpu Tongqiao < /em > Capsule improves cognitive impairment in rats with Wilson disease by inhibiting endoplasmic reticulum stress-mediated apoptosis pathway
CONCLUSION: HPTQ Capsule has neuroprotective effects in rat models of WD possibly by inhibiting ERS-mediated apoptosis pathway.PMID:38597435 | PMC:PMC11006687 | DOI:10.12122/j.issn.1673-4254.2024.03.05 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: X Zhang X Wang J Wang N Shao B Cai D Xie Source Type: research

< em > Huangpu Tongqiao < /em > Capsule improves cognitive impairment in rats with Wilson disease by inhibiting endoplasmic reticulum stress-mediated apoptosis pathway
CONCLUSION: HPTQ Capsule has neuroprotective effects in rat models of WD possibly by inhibiting ERS-mediated apoptosis pathway.PMID:38597435 | PMC:PMC11006687 | DOI:10.12122/j.issn.1673-4254.2024.03.05 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: X Zhang X Wang J Wang N Shao B Cai D Xie Source Type: research

< em > Huangpu Tongqiao < /em > Capsule improves cognitive impairment in rats with Wilson disease by inhibiting endoplasmic reticulum stress-mediated apoptosis pathway
CONCLUSION: HPTQ Capsule has neuroprotective effects in rat models of WD possibly by inhibiting ERS-mediated apoptosis pathway.PMID:38597435 | PMC:PMC11006687 | DOI:10.12122/j.issn.1673-4254.2024.03.05 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: X Zhang X Wang J Wang N Shao B Cai D Xie Source Type: research

< em > Huangpu Tongqiao < /em > Capsule improves cognitive impairment in rats with Wilson disease by inhibiting endoplasmic reticulum stress-mediated apoptosis pathway
CONCLUSION: HPTQ Capsule has neuroprotective effects in rat models of WD possibly by inhibiting ERS-mediated apoptosis pathway.PMID:38597435 | PMC:PMC11006687 | DOI:10.12122/j.issn.1673-4254.2024.03.05 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: X Zhang X Wang J Wang N Shao B Cai D Xie Source Type: research

< em > Huangpu Tongqiao < /em > Capsule improves cognitive impairment in rats with Wilson disease by inhibiting endoplasmic reticulum stress-mediated apoptosis pathway
CONCLUSION: HPTQ Capsule has neuroprotective effects in rat models of WD possibly by inhibiting ERS-mediated apoptosis pathway.PMID:38597435 | PMC:PMC11006687 | DOI:10.12122/j.issn.1673-4254.2024.03.05 (Source: Journal of Southern Medical University)
Source: Journal of Southern Medical University - April 10, 2024 Category: Universities & Medical Training Authors: X Zhang X Wang J Wang N Shao B Cai D Xie Source Type: research

Burden of Wilson Disease among patients and care partners in the United States: results from a cross-sectional survey
Conclusion: This study highlights the burden of WD experienced by patients and WD-CPs, with patients experiencing high treatment burden, comorbidity burden and healthcare resource utilization, and WD-CPs experiencing high impact of caring, including impact on employment and self-esteem.PMID:38571385 | DOI:10.1080/03007995.2024.2337684 (Source: Current Medical Research and Opinion)
Source: Current Medical Research and Opinion - April 4, 2024 Category: Research Authors: Jon Vlasnik M Janelle Cambron-Mellott Halley Costantino Mary Kunjappu Source Type: research

Exploring the Content Validity of the Unified Wilson Disease Rating Scale: Insights from Qualitative Research
ConclusionOverall, the findings from this study provide evidence for the content validity of the UWDRS Part  II and supportive evidence for the content validity of Part III. The UWDRS should be used in conjunction with additional clinical outcomes assessments, specifically those evaluating the hepatic and psychiatric signs/symptoms of WD, to provide a comprehensive evaluation of the WD patient experienc e. (Source: Advances in Therapy)
Source: Advances in Therapy - April 4, 2024 Category: Drugs & Pharmacology Source Type: research

Prevalence, Incidence, and Treatment Pattern of Wilson's Disease Using National Health Insurance Data From 2010-2020, Korea
CONCLUSION: The prevalence of WD in Korea is 3.06/100,000 and approximately 1,800 patients use medical services annually. A significant proportion of patients are diagnosed at the cirrhotic stage and not treated with Cu-chelating therapeutics, suggesting the need for early diagnosis and adequate treatment to improve prognosis.PMID:38565173 | DOI:10.3346/jkms.2024.39.e115 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 2, 2024 Category: Biomedical Science Authors: Eun Sun Jang Hwa Young Choi Moran Ki Bo Hyun Kim Kyung-Ah Kim Sook-Hyang Jeong Source Type: research

Prevalence, Incidence, and Treatment Pattern of Wilson's Disease Using National Health Insurance Data From 2010-2020, Korea
CONCLUSION: The prevalence of WD in Korea is 3.06/100,000 and approximately 1,800 patients use medical services annually. A significant proportion of patients are diagnosed at the cirrhotic stage and not treated with Cu-chelating therapeutics, suggesting the need for early diagnosis and adequate treatment to improve prognosis.PMID:38565173 | DOI:10.3346/jkms.2024.39.e115 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 2, 2024 Category: General Medicine Authors: Eun Sun Jang Hwa Young Choi Moran Ki Bo Hyun Kim Kyung-Ah Kim Sook-Hyang Jeong Source Type: research

Prevalence, Incidence, and Treatment Pattern of Wilson's Disease Using National Health Insurance Data From 2010-2020, Korea
CONCLUSION: The prevalence of WD in Korea is 3.06/100,000 and approximately 1,800 patients use medical services annually. A significant proportion of patients are diagnosed at the cirrhotic stage and not treated with Cu-chelating therapeutics, suggesting the need for early diagnosis and adequate treatment to improve prognosis.PMID:38565173 | DOI:10.3346/jkms.2024.39.e115 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 2, 2024 Category: Biomedical Science Authors: Eun Sun Jang Hwa Young Choi Moran Ki Bo Hyun Kim Kyung-Ah Kim Sook-Hyang Jeong Source Type: research

Prevalence, Incidence, and Treatment Pattern of Wilson's Disease Using National Health Insurance Data From 2010-2020, Korea
CONCLUSION: The prevalence of WD in Korea is 3.06/100,000 and approximately 1,800 patients use medical services annually. A significant proportion of patients are diagnosed at the cirrhotic stage and not treated with Cu-chelating therapeutics, suggesting the need for early diagnosis and adequate treatment to improve prognosis.PMID:38565173 | PMC:PMC10985507 | DOI:10.3346/jkms.2024.39.e115 (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 2, 2024 Category: General Medicine Authors: Eun Sun Jang Hwa Young Choi Moran Ki Bo Hyun Kim Kyung-Ah Kim Sook-Hyang Jeong Source Type: research

Prevalence, Incidence, and Treatment Pattern of Wilson's Disease Using National Health Insurance Data From 2010-2020, Korea
CONCLUSION: The prevalence of WD in Korea is 3.06/100,000 and approximately 1,800 patients use medical services annually. A significant proportion of patients are diagnosed at the cirrhotic stage and not treated with Cu-chelating therapeutics, suggesting the need for early diagnosis and adequate treatment to improve prognosis.PMID:38565173 | PMC:PMC10985507 | DOI:10.3346/jkms.2024.39.e115 (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - April 2, 2024 Category: Biomedical Science Authors: Eun Sun Jang Hwa Young Choi Moran Ki Bo Hyun Kim Kyung-Ah Kim Sook-Hyang Jeong Source Type: research