Human Oncogenic Viruses: Nature, Discovery, and Running Around in Circles
Wednesday Afternoon Lecture Series Annual George Khoury Lecture Dr. Chang is Distinguished Professor of Pathology in the Cancer Virology Program, University of Pittsburgh Cancer Institute. Her laboratory performs basic and applied research on viral oncogenesis with efforts focused in three areas: Merkel cell carcinoma and Merkel cell polyomavirus, the latter of which she discovered; Kaposi ’ s sarcoma-associated herpesvirus, the most common AIDS-associated malignancy; and new pathogen discovery. Seven viruses collectively comprise an important cause of cancer, particularly in less-developed countries and under conditions...
Source: Videocast - All Events - May 10, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Quasi-species Suppression of Viral Drug Resistance
NIH Director ’ s Wednesday Afternoon Lecture Series This is the annual George Khoury Lecture, which honors the memory of Dr. George Khoury (1943 – 1987), a highly regarded NIH virologist and caring mentor of the postdoctoral fellows in his laboratory. Dr. Karla Kirkegaard, Ph.D., is the Violetta L. Horton Research Professor of Genetics at the Stanford University School of Medicine. Her laboratory focuses on identification of dominant drug targets for antiviral design, such as small molecules that stabilize oligomeric assemblages. A past recipient of the NIH Director's Pioneer Award, Dr. Kirkegaard combines her interest...
Source: Videocast - All Events - March 1, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Dynamic Organelle Shape and Function During Herpesvirus Infection
Research in the Cristea laboratory focuses on characterizing mechanisms of cellular defense against viruses, as well as mechanisms used by viruses to manipulate these critical cellular processes. Towards these goals, her lab has promoted the integration of virology with proteomics and bioinformatics. The development of methods for studying virus-host protein interactions in space and time during the progression of an infection has allowed her group to bridge developments in mass spectrometry to important findings in virology.For more information go tohttps://oir.nih.gov/walsAir date: 6/16/2021 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 11, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

COVID-19: Developing a Vaccine During a Pandemic
COVID-19 Scientific Interest GroupDr. Barouch is the William Bosworth Castle Professor of Medicine and Professor of Immunology at Harvard Medical School and director of the Center for Virology and Vaccine Research at the Beth Israel Deaconess Medical Center. His talk will outline the current state of the COVID-19 vaccine field and will describe the development of the Ad26.COV2.S vaccine — a recombinant, replication-incompetent adenovirus serotype 26 (Ad26) vector encoding a full-length and stabilized SARS-CoV-2 spike protein.My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing n...
Source: Videocast - All Events - February 3, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

COVID 19 Vaccine Development
My laboratory focuses on studying the immunology and virology of HIV-1 infection and developing novel vaccine strategies. I have also recently demonstrated the therapeutic efficacy of potent monoclonal antibodies and the early seeding of the viral reservoir. My laboratory received three NIH U19 Integrated Preclinical/Clinical AIDS Vaccine Development (IPCAVD) program grants in 2005, 2008, and 2012 to construct alternative serotype adenovirus vaccine vectors, to explore their immunogenicity and protective efficacy in rhesus monkeys, and to advance optimal vaccine candidates into clinical trials. Four phase 1 clinical trials...
Source: Videocast - All Events - December 10, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

22nd Annual Norman P. Salzman Memorial Awards and Symposium in Basic and Clinical Virology
The Dr. Norman P. Salzman Memorial Fund was established in 1999 to present the annual Norman P. Salzman Memorial Symposium and Awards in Basic and Clinical Virology to outstanding postdoctoral fellows, graduate students and postbaccalaureate trainees working in intramural laboratories at the National Institutes of Health (NIH), U.S. Food and Drug Administration (FDA), Fort Detrick Laboratories, LEIDOS, United States Department of Agriculture (USDA) or Uniformed Services University of the Health Services (USUHS). The Symposium and Awards are hosted by the Foundation for the National Institutes of Health (FNIH), the NIH Viro...
Source: Videocast - All Events - October 19, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Norman P. Salzman Memorial Awards and Symposium in Basic and Clinical Virology 2020
The Dr. Norman P. Salzman Memorial Fund was established in 1999 to present the annual Norman P. Salzman Memorial Symposium and Awards in Basic and Clinical Virology to outstanding postdoctoral fellows, graduate students and postbaccalaureate trainees working in intramural laboratories at the National Institutes of Health (NIH), U.S. Food and Drug Administration (FDA), Fort Detrick Laboratories, LEIDOS, United States Department of Agriculture (USDA) or Uniformed Services University of the Health Services (USUHS). The Symposium and Awards are hosted by the Foundation for the National Institutes of Health (FNIH), the NIH Viro...
Source: Videocast - All Events - October 14, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

The Biomedical Research Response to COVID-19: A View from NIAID
NIH COVID-19 SIG Lecture Series NIAID has a long-standing dual mandate to maintain a robust portfolio of research in its key focus areas and to respond to emerging and re-emerging infectious diseases (EIDs). With this mandate, NIAID has also sought to improve EID-response preparedness, working in partnership with other U.S. government research entities, industry, academia, and international public-health organizations. This preparedness planning helped the institute respond rapidly to COVID-19. NIAID tapped existing coronavirus expertise and other assets to stand up research programs spanning basic virology and immunology ...
Source: Videocast - All Events - April 13, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

Dynamic organelle shape and function during herpesvirus infection
NIH Director's Wednesday Afternoon Lecture Series Research in the Cristea laboratory focuses on characterizing mechanisms of cellular defense against viruses, as well as mechanisms used by viruses to manipulate these critical cellular processes. Towards these goals, her lab has promoted the integration of virology with proteomics and bioinformatics. The development of methods for studying virus-host protein interactions in space and time during the progression of an infection has allowed her group to bridge developments in mass spectrometry to important findings in virology. For example, her laboratory has contributed to t...
Source: Videocast - All Events - October 10, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Therapeutic Interventions and Resistance Mechanisms
The HIV Dynamics and Replication Program (HIV DRP), Center for Cancer Research, NCI is organizing this conference to showcase the latest findings in the broad field of drug resistance in the context of infectious agents and cancer. An in-depth discussion of recent progress in our understanding of resistance mechanisms should lead to new insights into the development of more effective therapeutic interventions, which will aid international public health efforts. Confirmed speakers in this outstanding program include Silvia Bertagnolio (World Health Organization), Eric Freed (HIV DRP, NCI), Yoshihiro Kawaoka (University of T...
Source: Videocast - All Events - August 8, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

2018 Kinyoun Lecture - Opioids: Epidemic of our time and impact on infectious disease
Robert R. Redfield, M.D., director of the Centers for Disease Control and Prevention (CDC), will deliver the 2018 Joseph J. Kinyoun Memorial Lecture on the intersection between the national opioid crisis and the management of infectious diseases. Titled, “ Opioids: Epidemic of Our Time and Impact on Infectious Disease, ” Dr. Redfield ’ s talk will explore the impacts of the unprecedented use of opioids in the United States on the management of infectious diseases. While overdose remains the leading cause of death among people who use opioids, this population is also disproportionately affected by viral hepatitis, bac...
Source: Videocast - All Events - November 6, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

20th Annual Norman P. Salzman Memorial Award and Symposium in Virology
The Dr. Norman P. Salzman Memorial Fund was established in 1999 to present the annual Norman P. Salzman Memorial Symposium and Award in Virology to an outstanding Postdoctoral Fellow, Research Fellow or Clinical Fellow working in the field of virology at the NIH, the Center for Biologics Evaluation and Research at the U.S. Food and Drug Administration or Leidos community. The Symposium and Award are hosted by the FNIH and the NIH Virology Interest Group. The symposium highlights current research of eminent extramural and NIH intramural virologists. The Fund was established by Dr. Salzman ’ s family, colleagues and friend...
Source: Videocast - All Events - June 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Vesicular transmission of viral populations: strength in numbers
Director's Seminar Series Using interdisciplinary approaches from cell biology to virology to immunology, we investigate the strategies exploited by viruses to successfully transmit themselves among hosts. We recently discovered a novel form of viral transmission in which viruses are transmitted among hosts, not as single infectious units, but as populations of infectious units clustered inside vesicles. We have found this type of en masse transmission to be widespread in nature, taking place both within as well as between hosts and notably leading to enhanced viral infectivity, suppression of host immune responses and the...
Source: Videocast - All Events - February 12, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Joseph J. Kinyoun Memorial Lecture - Antibodies Against Ebola and Lassa: A Global Collaboration
Joseph J. Kinyoun Memorial Lecture 2017 Dr. Erica Ollmann Saphire, director of the Viral Hemorrhagic Fever Immunotherapeutic Consortium (VIC), will deliver the 2017 Joseph J. Kinyoun Memorial Lecture. Her talk, “ Antibodies Against Ebola and Lassa: A Global Collaboration, ” will explore the features of antibodies that protect against these deadly viruses and the ongoing need for scientists to collaborate in this research to establish a complete knowledge base. During the past three years, VIC researchers from dozens of labs on five continents have studied these protective antibodies. The VIC aims to fill critical knowl...
Source: Videocast - All Events - November 27, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video

Transcriptional Regulation of Neuroinflammation
NCI's Center for Cancer Research (CCR) Grand Rounds Dr. Lazarevic received her B.Sc. Microbiology degree from the University of Nottingham (UK) and Ph.D. degree in Molecular Virology and Microbiology from the University of Pittsburgh. Following her post-doctoral training in the laboratory of Dr. Laurie Glimcher at Harvard School of Public Health, Dr. Lazarevic was recruited as a tenure-track investigator in the Experimental Immunology Branch, CCR. Her laboratory is interested in how transcription factors regulate differentiation and effector function of CD4+ T helper (Th) cells in the context of autoimmune disorders with e...
Source: Videocast - All Events - November 13, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video