Fibrosis in Ulcerative Colitis and Mucosal Inflammation Fibrosis in Ulcerative Colitis and Mucosal Inflammation
This study investigated ulcerative colitis-associated fibrosis and its possible link to clinical parameters.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 15, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

InDex Pharmaceuticals Develops Oral Formulation of Cobitolimod
STOCKHOLM, May 4, 2018 -- (Healthcare Sales & Marketing Network) -- InDex Pharmaceuticals Holding AB (publ) today announced that it has developed a novel formulation of its lead drug candidate cobitolimod for oral administration, with targeted delivery to... Biopharmaceuticals, Gastroenterology InDex Pharmaceuticals, cobitolimod, ulcerative colitis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 4, 2018 Category: Pharmaceuticals Source Type: news

You Asked: What Is Inflammation, And Why Should I Care About It?
Your body can heal itself, which is pretty miraculous when you sit back and think about it. If you suffer a cut or infection—or if a disease, allergen or virus finds its way into you—your immune system reacts by sending specialized white blood cells to the affected area. These white blood cells can repair damage, stop the spread of infection or illness and in some cases eradicate the intruder. This whole response is called inflammation. “Inflammation is an activation of cells and cell-derived components that have the job of fighting invasions, and in some cases just sponging up or clearing out damaged cel...
Source: TIME: Health - April 11, 2018 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized healthytime medicine Source Type: news

Autofluorescence vs Chromoendoscopy for Dysplasia Surveillance in UC Autofluorescence vs Chromoendoscopy for Dysplasia Surveillance in UC
Autofluorescence imaging is inferior to chromoendoscopy for detecting neoplasms in patients with long-standing ulcerative colitis (UC), according to results from the FIND-UC trial.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - April 9, 2018 Category: Pathology Tags: Gastroenterology News Source Type: news

Analysis challenges link between pain medications and inflammatory bowel disease
(Wiley) Contrary to generally accepted belief, a recent review and analysis of published studies did not reveal a consistent association between the use of nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen and exacerbation of Crohn's disease and ulcerative colitis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 5, 2018 Category: International Medicine & Public Health Source Type: news

Tofacitinib and Biological Therapies for Ulcerative Colitis Tofacitinib and Biological Therapies for Ulcerative Colitis
Tofacitinib is currently under review as induction and/or maintenance therapy for adult patients with moderate-to-severe ulcerative colitis. How does it compare with other biologics?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 27, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

EMA Committee Backs Remicade Biosimilar Zessly EMA Committee Backs Remicade Biosimilar Zessly
The committee favors marketing the infliximab biosimilar product Zessly for treatment of rheumatoid arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and psoriasis.International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 24, 2018 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news

Higher dose of Arena Pharma's bowel disease drug meets study goal
(Reuters) - Arena Pharmaceuticals Inc said on Monday a higher dose of its experimental drug succeeded in improving symptoms associated with ulcerative colitis, a chronic bowel disease, in a mid-stage study. (Source: Reuters: Health)
Source: Reuters: Health - March 19, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

FDA Panel Backs Proposed Tofacitinib Dosing for Ulcerative Colitis FDA Panel Backs Proposed Tofacitinib Dosing for Ulcerative Colitis
Pfizer scored a win in its efforts to move forward a delayed application for new use of its rheumatoid arthritis drug for treating chronic inflammation of the colon.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 9, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

FDA Panel Backs Higher Tofacitinib Dose in Ulcerative Colitis
(MedPage Today) -- Drugmaker seeks new indication for oral JAK inhibitor (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 8, 2018 Category: Gastroenterology Source Type: news

FDA panel backs Pfizer's Xeljanz as bowel disease treatment
(Reuters) - Pfizer Inc's Xeljanz should be approved to treat patients with moderate to severe ulcerative colitis, a chronic bowel disease, a U.S. Food and Drug Administration (FDA) advisory committee concluded on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - March 8, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Diverticulitis vs Ulcerative Colitis UC
Diverticular Disease (Diverticulitis) vs. Ulcerative Colitis (UC) (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - March 6, 2018 Category: General Medicine Source Type: news

First- and Second-line Therapy for Moderate-severe UC First- and Second-line Therapy for Moderate-severe UC
This study assessed the comparative efficacy and safety of different therapies as first-line and second-line agents for moderate-severe ulcerative colitis. What is the optimal regimen?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 1, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Vedolizumab Emerges as Option in IBD After Anti-TNF Failure Vedolizumab Emerges as Option in IBD After Anti-TNF Failure
The management of anti-TNF-resistant patients is an important clinical challenge, but new data suggest that vedolizumab helps mucosal healing in Crohn's disease and ulcerative colitis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 16, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Medical cannabis significantly safer for elderly with chronic pain than Opioids
(American Associates, Ben-Gurion University of the Negev) The new study, published in The European Journal of Internal Medicine, found cannabis therapy is safe and efficacious for elderly patients who are seeking to address cancer symptoms, Parkinson's disease, post-traumatic stress disorder, ulcerative colitis, Crohn's disease, multiple sclerosis, and other medical issues. After six months, more than 18 percent of patients surveyed had stopped using opioid analgesics or had reduced their dosage. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 13, 2018 Category: International Medicine & Public Health Source Type: news

Efficacy of Fecal Microbiota Transplant in Refractory UC Efficacy of Fecal Microbiota Transplant in Refractory UC
Could the microbial composition of donor stools influence why some therapy refractory ulcerative colitis patients respond well to fecal transplantation, while others do not?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 9, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Medical News Today: 10 rashes caused by ulcerative colitis
This article looks at skin conditions that are related to ulcerative colitis, including psoriasis, vitiligo, and hives. Learn about causes and prevention. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 18, 2018 Category: Consumer Health News Tags: Dermatology Source Type: news

Colon Cancer Symptoms vs Ulcerative Colitis
Colon Cancer Symptoms vs. Ulcerative Colitis Differences and Similarities (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 12, 2018 Category: General Medicine Source Type: news

Tofacitinib: Emerging Therapy for Ulcerative Colitis? Tofacitinib: Emerging Therapy for Ulcerative Colitis?
Will tofacitinib change the treatment landscape of ulcerative colitis?Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 11, 2018 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

Biologicals not cost effective for ulcerative colitis
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - January 1, 2018 Category: Drugs & Pharmacology Source Type: news

One third of antidepressants are prescribed for something else
It was when he became a father that Michael Briggs resolved to somehow bring his ulcerative colitis under control. (Source: CNN.com - Health)
Source: CNN.com - Health - December 19, 2017 Category: Consumer Health News Source Type: news

One-third of antidepressants are prescribed for something else
It was when he became a father that Michael Briggs resolved to somehow bring his ulcerative colitis under control. (Source: CNN.com - Health)
Source: CNN.com - Health - December 19, 2017 Category: Consumer Health News Source Type: news

Ulcerative colitis symptoms: Painful joints and red eyes signs of a flare up
ULCERATIVE COLITIS symptoms include diarrhoea and tummy pain. Here are the other signs you could have the inflammatory bowel condition. (Source: Daily Express - Health)
Source: Daily Express - Health - December 12, 2017 Category: Consumer Health News Source Type: news

Persistent diarrhoea and painful joints? The symptoms of ulcerative colitis REVEALED
ULCERATIVE COLITIS symptoms include diarrhoea and tummy pain. Here are the other signs you could have the inflammatory bowel condition. (Source: Daily Express - Health)
Source: Daily Express - Health - December 12, 2017 Category: Consumer Health News Source Type: news

MIT Researchers Land Deal For Needle-Free Drug Injector
CBS Local — Scared of needles? Can’t stand all the pinpricks from taking medication or diabetes tests? Startup company Portal Instruments has landed a major deal to bring their needle-free solution to market in a move that could change the way people take medicine forever. The tech startup, which was created by MIT researchers in 2012, has reached a deal with Japanese pharmaceutical company Takeda to help develop the “PRIME” injector and bring it to the market. MIT says Portal will receive an undisclosed payment for their invention, with the potential to earn up to $100 million for reaching cer...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 12, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Chris Melore drug injector Local TV MIT Needles Portal Instruments talkers Source Type: news

Caroline ’s life-changing backpack
Caroline at a recent appointment getting her height and weight checked When it comes to being active, there is no stopping Caroline Spaulding. Whether speaking on behalf of inflammatory bowel disease (IBD) legislation on Capitol Hill, performing in a ballet recital or lacing up her cleats for a soccer game, Caroline, 13, is a force to be reckoned with. Her strong sense of determination is what carried her through her Crohn’s disease diagnosis and the 12-week, formula-only treatment plan — exclusive enteral nutrition (EEN) — that followed. “When I was nine years old, I stopped growing and started los...
Source: Thrive, Children's Hospital Boston - December 8, 2017 Category: Pediatrics Authors: Maureen McCarthy Tags: Diseases & Conditions Our Patients’ Stories Bridget Hron Crohn's disease Exclusive Enteral Nutrition Inflammatory Bowel Disease Center Jocelyn Silvester Naamah Zitomersky Source Type: news

How a New Device Could Ease the Pain of Biologics
Portal Instruments, a new medical device startup out of Cambridge, MA, announced a partnership this week with Japanese pharmaceutical giant Takeda to develop a new needle-free drug delivery device to help treat chronic conditions. The new device has the potential to treat a wide range of conditions that require drugs to be injected through a needle, specifically GI diseases like ulcerative colitis and Crohn's disease. The partnership will combine Portal's delivery device with Takeda's investigational or approved biologic medicines. The technology is designed to deliver drugs through the use of a pressurized liqui...
Source: MDDI - December 8, 2017 Category: Medical Devices Authors: Kristopher Sturgis Tags: R & D Source Type: news

Medical News Today: Remedies for ulcerative colitis constipation
Some people with ulcerative colitis experience frequent constipation. Learn about the treatment options, including magnesium and castor oil. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 7, 2017 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Changing gut bacteria in Crohn ’s disease
A single enzyme altered the mix of bacteria in the guts of mice and led to inflammatory bowel disease. The study suggests a potential treatment target for diseases such as Crohn ’s disease and ulcerative colitis. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 5, 2017 Category: Consumer Health News Source Type: news

Ulcerative Colitis
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - December 4, 2017 Category: General Medicine Source Type: news

Mucosal healing: An objective measure of disease activity?
(Boston University School of Medicine) The absence of inflammatory and ulcerative lesions in all segments of the colon, also known as mucosal healing, should be the end goal in treating patients with ulcerative colitis according to an editorial in the journal Gastrointestinal Endoscopy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2017 Category: International Medicine & Public Health Source Type: news

Medical News Today: What you need to know about pancolitis
A look at pancolitis, a form of ulcerative colitis affecting the intestine. Included is information on flare-ups and complications of the condition. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 18, 2017 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Medical News Today: What is left-sided colitis?
Left-sided colitis is a form of ulcerative colitis that affects the left side of the colon, causing a range of gastrointestinal symptoms. Learn more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 8, 2017 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Takeda, Portal Instruments ink $100m deal to combine biologics and needle-free drug delivery
Takeda Pharmaceutical (TYO:4502) and Portal Instruments said today that the pair inked a collaboration to develop and commercialize Portal’s needle-free drug delivery device with Takeda’s biologic medicines. The first development program is slated to combine Takeda’s monoclonal antibody for adults with moderately- to severely-active ulcerative colitis or Crohn’s disease with Portal’s technology. The investigational therapy is currently administered through intravenous infusion, according to Takeda. Get the full story at our sister site, Drug Delivery Business News. The post Take...
Source: Mass Device - November 7, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Pharmaceuticals Wall Street Beat portal instruments Takeda Pharmaceuticals Source Type: news

What Causes White Nails?
Discussion The nail matrix covers the area of the nail plate, and extends proximally in a crescent moon shape with the edges of the crescent extending proximally and inferiorly toward the underlying bone. The nail matrix is a multilayered epithelium that physiologically produces keratinization and gives rise to the nail plate. The distal matrix forms the lower 2/3s of the nail plate and the proximal matrix forms the upper 1/3 of the nail plate. the thickness of the nail plate is proportion to the matrix’s thickness. The nail plate’s free edge contour follows the shape of the nail’s lunula. Melanocytes occ...
Source: PediatricEducation.org - November 6, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Continuous Clinical Response in Ulcerative Colitis Continuous Clinical Response in Ulcerative Colitis
Continuous clinical response has emerged as a useful target in the management of ulcerative colitis. Can it be feasibly integrated into clinical practice as a patient-reported outcome?Clinical Gastroenterology and Hepatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 10, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Seres reports positive Phase Ib trial results of SER-287 in UC patients
US-based Seres Therapeutics has reported positive topline results from a Phase Ib placebo-controlled induction trial of SER-287 in patients with mild-to-moderate ulcerative colitis (UC), who were failing current therapies. (Source: Drug Development Technology)
Source: Drug Development Technology - October 3, 2017 Category: Pharmaceuticals Source Type: news

Belfast bodybuilder left mute by six stone weight loss
Terri Keith, 30, of Belfast, went from a size 16 to a size 6 in just 10 months but The weight loss left her with malnutrition and made  her ulcerative colitis worse. Now she is a champion bodybuilder. (Source: the Mail online | Health)
Source: the Mail online | Health - September 25, 2017 Category: Consumer Health News Source Type: news

Inflammatory Bowel Disease May Raise Cancer Risk in Kids
Researchers think chronic inflammation in gastrointestinal tract may be driving forceSource: HealthDay Related MedlinePlus Pages: Cancer in Children, Crohn's Disease, Ulcerative Colitis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - September 21, 2017 Category: Consumer Health News Source Type: news

Ulcerative Colitis Quiz: Diet, Symptoms & Treatment
Title: Ulcerative Colitis Quiz: Diet, Symptoms& TreatmentCategory: MedicineNet QuizCreated: 12/18/2012 12:00:00 AMLast Editorial Review: 9/20/2017 1:04:13 PM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - September 20, 2017 Category: Nutrition Source Type: news

The Efficacy of Probiotics in Inflammatory Bowel Disease The Efficacy of Probiotics in Inflammatory Bowel Disease
This study examined the efficacy of probiotics in inducing and maintaining remission in ulcerative colitis and Crohn disease, as well as preventing relapse in post-operative CD.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 12, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Risk for Pouch Cancer Not Elevated After Ileal Pouch-anal Anastomosis for UC Risk for Pouch Cancer Not Elevated After Ileal Pouch-anal Anastomosis for UC
Patients who undergo ileal pouch-anal anastomosis (IPAA) after colorectal excision for ulcerative colitis (UC) do not have an increased risk of pouch or extraintestinal cancers, researchers from Denmark report.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 29, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Asthma Tied to Later Inflammatory Bowel Disease
Findings for Crohn's and early - or late - onset ulcerative colitis (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - August 25, 2017 Category: Respiratory Medicine Tags: Gastroenterology, Internal Medicine, Allergy, Pathology, Pulmonology, Journal, Source Type: news

Ulcerative colitis breakthrough: THIS test for bowel disease could revolutionise diagnosis
ULCERATIVE colitis is a form of inflammatory bowel disease - a condition which causes inflammation of the bowel and painful symptoms. (Source: Daily Express - Health)
Source: Daily Express - Health - August 24, 2017 Category: Consumer Health News Source Type: news

Fecal Transplantation for Remission of Ulcerative Colitis Fecal Transplantation for Remission of Ulcerative Colitis
Fecal microbiota transplantation is emerging as a novel therapy for the induction of remission in active ulcerative colitis.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 24, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Blood test for colitis screening using infrared technology could reduce dependence on colonoscopy
(Georgia State University) A fast, simple blood test for ulcerative colitis using infrared spectroscopy could provide a cheaper, less invasive alternative for screening compared to colonoscopy, which is now the predominant test, according to a study between the Department of Physics and Astronomy and the Institute for Biomedical Sciences at Georgia State University. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 23, 2017 Category: International Medicine & Public Health Source Type: news

Takeda submits NDA for Vedolizumab to treat moderate-to-severe UC in Japan
Takeda Pharmaceutical has filed a new drug application (NDA) for vedolizumab with Japan ’s Ministry of Health, Labour and Welfare to treat adult patients with moderately to severely active ulcerative colitis (UC). (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - August 22, 2017 Category: Pharmaceuticals Source Type: news

NIH grant to biomedical scientist will advance research on inflammatory bowel disease
(University of California - Riverside) Declan McCole, a biomedical scientist at the University of California, Riverside, has received a $1.83 million grant from the National Institutes of Health to identify how the loss of a protective barrier in the intestine contributes to inflammatory bowel disease (IBD). IBD is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 11, 2017 Category: International Medicine & Public Health Source Type: news

Ulcerative Colitis vs. Crohn ’s Disease – Similarities And Differences
Under normal circumstances, our immune system does its job of protecting the body from infection. However, in people who (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - August 7, 2017 Category: Consumer Health News Source Type: news