Genetic Risk Factors for C. difficile in Ulcerative ColitisGenetic Risk Factors for C. difficile in Ulcerative Colitis
Are some patients with ulcerative colitis more susceptible to developing C. difficile infection than others and, if so, are genetics to blame? Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 4, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Invitation to Late-stage pipeline event Tuesday, 1 October 2013
The Roche Investor Relations team would like to invite you to a Late-stage pipeline event that will take place in London on 1 October 2013 starting at 2.30pm local time. The event will provide an opportunity to discuss clinical data and development plans for key late-stage compounds in the Roche development pipeline, including lampalizumab (anti-factor D) in dry AMD, etrolizumab in ulcerative colitis and selected oncology compounds. (Source: Roche Investor Update)
Source: Roche Investor Update - August 30, 2013 Category: Pharmaceuticals Source Type: news

Heat Waves Tied to Flare-Ups of Digestive Illness
Flare-ups of inflammatory bowel disease and "stomach bugs" may be more common during and immediately after heat waves, a new study suggests.Source: Reuters Health Related MedlinePlus Pages: Crohn's Disease, Gastroenteritis, Ulcerative Colitis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - August 29, 2013 Category: Consumer Health News Source Type: news

New report shows improvement for patients with IBD following biological therapy
Over half of patients saw an improvement after being treated with biological therapies for inflammatory bowel disease (IBD). Data from the first national report of biological therapies shows that 62% of adult patients and 73% of paediatric patients saw the severity of their disease decrease after 12 weeks of treatment with biological therapy. IBD affects approximately 240,000 people in the UK[1] and patients with Ulcerative Colitis (UC) and Crohn's Disease (CD) will often require surgery during their lifetime... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 29, 2013 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Vedolizumab Eases Severe IBD in Two Trials (CME/CE)
(MedPage Today) -- The monoclonal antibody vedolizumab was effective in many patients with active, refractory inflammatory bowel disease, although benefits were more pronounced for the subgroup of those with ulcerative colitis, two randomized trials found. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - August 22, 2013 Category: Gastroenterology Source Type: news

Crohn's and colitis drug effective in trials
Two studies published this week in the New England Journal of Medicine could bring relief to people suffering from Crohn's disease and ulcerative colitis. They report two international phase 3 clinical trials called GEMINI I and GEMINI II that found the investigational drug vedolizumab is an effective treatment for patients with the inflammatory bowel conditions for whom other treatments have not worked... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 22, 2013 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

How to Have a Confident Social Life With IBD
Life with inflammatory bowel disease can mean you have really unpleasant symptoms with little or no warning. A few people who’ve had Crohn’s disease and ulcerative colitis offer tips for keeping an active social life. (Source: WebMD Health)
Source: WebMD Health - August 21, 2013 Category: Consumer Health News Source Type: news

Simponi (Golimumab) - Treatment for Ulcerative Colitis (UC)
Simponi (golimumab) is a subcutaneous injection for the treatment of adult patients living with ulcerative colitis (UC). The drug was discovered and developed by Janssen Biotech. (Source: Drug Development Technology)
Source: Drug Development Technology - July 30, 2013 Category: Pharmaceuticals Source Type: news

EU Regulators Recommend Golimumab for Ulcerative ColitisEU Regulators Recommend Golimumab for Ulcerative Colitis
The FDA approved the anti-inflammatory drug for this indication just 2 months earlier. International Approvals (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 26, 2013 Category: Consumer Health News Tags: Gastroenterology News Alert Source Type: news

Pop Quiz: GI Concerns
Ulcerative colitis, pregnancy...and prednisone? How would you handle a UC flare in this patient? (Source: Consultant Live)
Source: Consultant Live - July 25, 2013 Category: Primary Care Source Type: news

Colon Capsule Endoscope for Ulcerative ColitisColon Capsule Endoscope for Ulcerative Colitis
How effective are second-generation colon capsule endoscopes at evaluating the severity of mucosal inflammation in patients with ulcerative colitis? Journal of Gastroenterology and Hepatology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 22, 2013 Category: Gastroenterology Tags: Gastroenterology Journal Article Source Type: news

Ulcerative Colitis: Symptoms and Treatment
Here are tips for preventing and managing inflammatory bowel disease. (Source: U.S. News - Health)
Source: U.S. News - Health - July 13, 2013 Category: Consumer Health News Source Type: news

Infliximab Effective for Rescue in Steroid-Refractory ColitisInfliximab Effective for Rescue in Steroid-Refractory Colitis
Infliximab is effective rescue therapy - both short- and long-term - for a steroid-resistant attack of ulcerative colitis (UC), according to a Swedish study. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 12, 2013 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Infliximab Better Than Cyclosporine in Refractory ColitisInfliximab Better Than Cyclosporine in Refractory Colitis
Infliximab appears to be better than cyclosporine as salvage therapy for steroid-refractory acute severe ulcerative colitis (UC), researchers from Australia report. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 6, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Wegener's Granulomatosis Mimicking Severe Ulcerative ColitisWegener's Granulomatosis Mimicking Severe Ulcerative Colitis
A 20-year old woman in septic shock presented with a pancolonic, superficial microulceration suggesting ulcerative colitis. What did surgery reveal? Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 5, 2013 Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news

The Effects Of Exercise On Ulcerative Colitis
A new study indicates that aerobic exercise can lessen - or worsen - the symptoms of inflammatory bowel diseases such as ulcerative colitis, depending on the circumstances under which the exercise is undertaken. The researchers found that, in contrast to their sedentary peers, mice allowed to run freely on an exercise wheel for six weeks had fewer symptoms of colitis after exposure to a chemical agent that induces colitis symptoms in mice... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 5, 2013 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Team explores the effects of exercise on ulcerative colitis
(University of Illinois at Urbana-Champaign) Aerobic exercise can lessen -- or worsen -- the symptoms of inflammatory bowel diseases such as ulcerative colitis, depending on the circumstances under which the exercise is undertaken, researchers report. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 2, 2013 Category: Global & Universal Source Type: news

Pouchitis: A Practical GuidePouchitis: A Practical Guide
Patients with ulcerative colitis who have undergone colectomy with ileal pouch-anal anastomosis often develop pouchitis. How is it diagnosed and best treated? Frontline Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 28, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

NICE guidance to eradicate the postcode lottery of treatment for a type of severe bowel disease
For the first time ever, doctors have a clear guideline from NICE to make it easier for them to treat people with ulcerative colitis. More ..... (Source: NHS Networks)
Source: NHS Networks - June 28, 2013 Category: UK Health Authors: Maria Axford Source Type: news

Mesalamine Suppositories Helpful in Ulcerative ColitisMesalamine Suppositories Helpful in Ulcerative Colitis
Mesalamine (mesalazine) suppositories are significantly more effective than placebo for rectal inflammation in patients with ulcerative colitis (UC), Japanese researchers say. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 25, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Takeda Seeks to Remedy Crohn's Disease, Ulcerative Colitis in US
Takeda Submits Biologics License Application for a New Investigational Drug Vedolizumab, in Moderately to Severely Active Crohn's Disease and Ulcerative Colitis in the United States (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - June 24, 2013 Category: Pharmaceuticals Authors: Pharma Manufacturing Source Type: news

What Causes Lymphocytosis?
Discussion Lymphocytes are an important part of the cellular and humoral immunity. Absolute lymphocyte count (ALC) is usually used to determine ranges of normal for lymphocytes. The ALC is higher in neonates and young children (up to 8000 cells/microL) but in those> 12 years of age is normally> 4000 cells/microL. Lymphopenia is usually defined as
Source: PediatricEducation.org - June 24, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Inflammatory Bowel Disease and Colorectal...
Inflammatory bowel disease, often characterized by conditions such as ulcerative colitis and Chron's disease, increases the risk of developing colorectal cancer. (Source: About.com Colon Cancer)
Source: About.com Colon Cancer - June 19, 2013 Category: Cancer & Oncology Authors: coloncancer.guide at about.com Tags: health Source Type: news

Ulcerative ColitisUlcerative Colitis
What are the most effective strategies for maintaining remission of ulcerative colitis? Expert Review of Gastroenterology and Hepatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 17, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

BMI and the Risk for Crohn's Disease and Ulcerative ColitisBMI and the Risk for Crohn's Disease and Ulcerative Colitis
What does the latest science tell us about the possible connection between BMI and the development of Crohn's disease or ulcerative colitis? The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 13, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Novel Strategy for Inflammatory Bowel DiseaseNovel Strategy for Inflammatory Bowel Disease
Learn more about the role of adhesion molecules and leukocyte recruitment both in ulcerative colitis and Crohn disease. Expert Review of Clinical Immunology (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - June 12, 2013 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology Journal Article Source Type: news

Ulcerative Colitis Quiz: Test Your IQ of Digestive Diseases
Title: Ulcerative Colitis Quiz: Test Your IQ of Digestive DiseasesCategory: MedicineNet QuizCreated: 12/18/2012 1:08:00 PMLast Editorial Review: 6/10/2013 2:15:52 PM (Source: MedicineNet Crohn's Disease General)
Source: MedicineNet Crohn's Disease General - June 10, 2013 Category: Gastroenterology Source Type: news

Autotaxin/Lysophospholipase D Expression in Intestinal DamageAutotaxin/Lysophospholipase D Expression in Intestinal Damage
Could the LPA-producing enzyme autotaxin be a possible target for treatment of gastrointestinal conditions such as IBD, Crohn's disease, and ulcerative colitis? Laboratory Investigation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 7, 2013 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Risk Of Melanoma Increased By Inflammatory Bowel Disease
Patients with inflammatory bowel disease(IBD) are at higher risk of melanoma, a form of skin cancer, report researchers at Mayo Clinic. Researchers found that IBD is associated with a 37 percent greater risk for the disease. The findings were presented at the Digestive Disease Week 2013 conference in Orlando, Fla. More than 1.5 million Americans have Crohn's disease or ulcerative colitis (UC), the most common forms of inflammatory bowel disease... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 22, 2013 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Impact of Mucosal Healing on Outcomes in Ulcerative ColitisImpact of Mucosal Healing on Outcomes in Ulcerative Colitis
What is the best way to achieve mucosal healing in patients with ulcerative colitis treated with anti-TNF agents, and what is the long-term outcome generally like in this subset of patients? Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 21, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Roche's etrolizumab meets primary endpoint of clinical remission in moderate to severely active ulcerative colitis at week 10
Roche announced today that the EUCALYPTUS phase II induction study of etrolizumab in patients with moderate-to-severely active ulcerative colitis (UC) met its primary endpoint of clinical remission at week 10. Additionally, the data showed etrolizumab was well tolerated with no clinically significant safety concerns. Findings were presented this weekend at the 2013 Digestive Disease Week meeting held in Orlando, Fla. (Source: Roche Investor Update)
Source: Roche Investor Update - May 18, 2013 Category: Pharmaceuticals Source Type: news

Simponi Approved for Ulcerative Colitis
Blocks process that contributes to abnormal inflammation (Source: WebMD Health)
Source: WebMD Health - May 16, 2013 Category: Consumer Health News Source Type: news

Simponi Approved for Ulcerative Colitis
Title: Simponi Approved for Ulcerative ColitisCategory: Health NewsCreated: 5/15/2013 6:36:00 PMLast Editorial Review: 5/16/2013 12:00:00 AM (Source: MedicineNet Crohn's Disease General)
Source: MedicineNet Crohn's Disease General - May 16, 2013 Category: Gastroenterology Source Type: news

FDA Approves Simponi to Treat Ulcerative Colitis
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - May 16, 2013 Category: Journals (General) Source Type: news

Simponi OK'd for Ulcerative Colitis
(MedPage Today) -- SILVER SPRING, Md. -- The biologic drug golimumab (Simponi) may be used to treat moderate to severe ulcerative colitis, the FDA said Wednesday. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - May 16, 2013 Category: Rheumatology Source Type: news

FDA Approves New Indication for SimponiFDA Approves New Indication for Simponi
The agency has approved golimumab (Simponi) injection to treat adults with moderate to severe refractory ulcerative colitis. FDA Approvals (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 16, 2013 Category: Consumer Health News Tags: Gastroenterology News Alert Source Type: news

FDA approves J&J's Simponi to treat ulcerative colitis
(Reuters) - The Food and Drug Administration has approved Johnson & Johnson's drug Simponi for patients with moderate to severe ulcerative colitis, an inflammatory disease affecting the colon. (Source: Reuters: Health)
Source: Reuters: Health - May 15, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

FDA approves Simponi to treat ulcerative colitis
The U.S. Food and Drug Administration today approved a new use for Simponi (golimumab) injection to treat adults with moderate to severe ulcerative colitis. (Source: Food and Drug Administration)
Source: Food and Drug Administration - May 15, 2013 Category: American Health Source Type: news

Flu Vaccine Safe for Kids with Crohn'S, Colitis
It may even reduce their bowel symptoms, researchers say Source: HealthDay Related MedlinePlus Pages: Crohn's Disease, Flu, Ulcerative Colitis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 6, 2013 Category: Consumer Health News Source Type: news

PET/CT Enhance Inflammatory Bowel Disease Detection
Inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, may be detected and monitored more effectively in the future with positron emission tomography/computed tomography (PET/CT), according to research published in the May issue of The Journal of Nuclear Medicine. Typically assessed by endoscopic and histologic evaluations, investigators demonstrated the ability of PET/CT to identify lesions along the complete intestinal wall that could be missed with traditional imaging techniques... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 5, 2013 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Patients With Inflammatory Diseases Often Prescribed Biologic Agents Which May Cause Acute Liver Injury
A commonly used class of biologic response modifying drugs can cause acute liver injury with elevated liver enzymes, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. Patients with inflammatory diseases such as Chron's disease or ulcerative colitis often are prescribed tumor necrosis factor-alpha (TNF-α) antagonists, which modify the body's response to infection. Patients with inflammatory arthropathies and selected dermatological diseases are also candidates to receive such compounds... (Source: Health...
Source: Health News from Medical News Today - May 1, 2013 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Inflammatory bowel disease detection enhanced with PET/CT
(Society of Nuclear Medicine) Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, may be detected and monitored more effectively in the future with positron emission tomography/computed tomography, according to research published in the May issue of The Journal of Nuclear Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 1, 2013 Category: Global & Universal Source Type: news

Role of Anti-TNF in the Management of Ulcerative ColitisRole of Anti-TNF in the Management of Ulcerative Colitis
How effective and safe are anti-TNF agents in the treatment of ulcerative colitis? Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 30, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Immune Cells Taught By Thymus To Ignore Vital Gut Bacteria
The tiny thymus teaches the immune system to ignore the teeming, foreign bacteria in the gut that helps you digest and absorb food, researchers say. When immune cells recognize essential gut bacteria as foreign, inflammatory bowel disease such as ulcerative colitis and Crohn's disease can be the painful, debilitating result. In a study published in the journal Nature, researchers show that the regulatory T cells, or Tregs, that keep this from happening in most of us come from the tiny immune organ nestled near the heart, said Dr... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 30, 2013 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

Health Care’s ‘Dirty Little Secret’: No One May Be Coordinating Care
Betsy Gabay saw a rotating cast of at least 14 doctors when she was hospitalized at New York Hospital Queens for almost four weeks last year for a flare-up of ulcerative colitis. (Source: RWJF News Digest - Quality/Equality)
Source: RWJF News Digest - Quality/Equality - April 30, 2013 Category: Health Management Source Type: news

Galapagos commences Phase IIa ulcerative colitis study of GLPG0974
Galapagos has commenced a Phase IIa study of GLPG0974, which is designed to provide a novel mode of action for the treatment of ulcerative colitis. (Source: Drug Development Technology)
Source: Drug Development Technology - April 25, 2013 Category: Pharmaceuticals Source Type: news

Fecal Transplant Studied for Kids with Bowel Disease
Symptoms of ulcerative colitis disappeared for one-third of patients after process Source: HealthDay Related MedlinePlus Pages: Children's Health, Ulcerative Colitis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 17, 2013 Category: Consumer Health News Source Type: news

Fecal Microbial Transplantation May Treat Ulcerative ColitisFecal Microbial Transplantation May Treat Ulcerative Colitis
Fecal microbial transplantation via enema may be effective, tolerable, and feasible for treating kids with ulcerative colitis, according to a study showing acceptable, self-limiting adverse events. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 12, 2013 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Clinical Trial Finds Fecal Microbial Transplantation An Effective Treatment For Ulcerative Colitis
A Spectrum Health clinical trial has found that fecal microbial transplantation (FMT) has resulted in the improvement or absence of symptoms in most pediatric patients with active ulcerative colitis. The phase I clinical trial of the procedure was conducted by members of the Pediatric Specialty Department of the Spectrum Health Medical Group at Helen DeVos Children's Hospital, the first in the country to study FMT in children... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 9, 2013 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news