Podcast: Immunosuppressive treatment for people with proliferative lupus nephritis
Systemic lupus erythematosus, or SLE, is an autoimmune disease that can affect any part of the body. About half the people with it develop lupus nephritis. In the June 2018 update of their Cochrane Review, David Tunnicliffe from the Centre for Kidney Research in the Children ’s Hospital at Westmead and the University of Sydney’s School of Public Health in Australia and colleagues brought together the studies that have tested a range of treatments." Lupus nephritis is a serious condition, leading to end-stage kidney disease in 15% of patients after 10 years. It mainly affects women of child-bearing age, and is more comm...
Source: Cochrane News and Events - May 30, 2019 Category: Information Technology Authors: Lydia Parsonson Source Type: news
Update on the Use of Tacrolimus in Pediatrics Update on the Use of Tacrolimus in Pediatrics
This article provides an update for its use in children.Pediatric Pharmacotherapy (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 18, 2019 Category: Allergy & Immunology Tags: Pediatrics Journal Article Source Type: news
tacrolimus ointment (Protopic)
Title: tacrolimus ointment (Protopic)Category: MedicationsCreated: 1/21/2002 12:00:00 AMLast Editorial Review: 3/1/2019 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - March 1, 2019 Category: Dermatology Source Type: news
Reprogramming the wonder drug rapamycin allows creation of new small-molecule drugs
(University of Helsinki) In the new study, the authors aimed to reprogram rapamycin by keeping the parts of rapamycin and tacrolimus that bind FKBP12 and changing the remaining half of the molecule in order to target completely new disease-associated proteins beyond mTOR and calcineurin. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 27, 2019 Category: International Medicine & Public Health Source Type: news
FDA Approves New Indication for Envarsus XR (tacrolimus extended-release tablets)
COPENHAGEN, Denmark, Dec. 19, 2018 /PRNewswire/ -- Veloxis Pharmaceuticals announced today that the U.S. Food& Drug Administration (FDA) approved a new indication for Envarsus XR (tacrolimus extended-release tablets) to prevent organ rejection... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - December 19, 2018 Category: Drugs & Pharmacology Source Type: news
How a Tiny Device Is Making a Big Difference for Pediatric Transplant Patients
Imagine being a pediatric kidney transplant patient and having to miss school or extracurricular activities because of clinic appointments and routine blood tests. Now imagine being offered a take-home kit that has everything you and your caregivers need to collect a blood sample at home that can be shipped to a lab.
For patients like 14-year-old Josh Knapp, a kidney transplant patient in England, that choice became a reality, thanks to an initiative at Nottingham University Hospital designed to facilitate easier therapeutic drug monitoring of tacrolimus and creatinine. Made specifically for pediatric transplant patients, ...
Source: MDDI - December 14, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: IVD Source Type: news
Tacrolimus: A Role in Lupus?
(MedPage Today) -- Successful add-on treatment in small European study (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - November 6, 2018 Category: Primary Care Source Type: news
Recurrent PBC Tied to Higher Risk of Liver Graft Loss, Death (CME/CE)
(MedPage Today) -- Severe cholestasis, use of tacrolimus predicted post-graft disease recurrence (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - October 9, 2018 Category: Surgery Source Type: news
Rituximab Over Tacrolimus in Steroid-Dependent Nephrotic Syndrome? Rituximab Over Tacrolimus in Steroid-Dependent Nephrotic Syndrome?
Dr Desai reviews recent trials comparing steroid-sparing agents used to treat corticosteroid-dependent children with nephrotic syndrome.Medscape Nephrology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 8, 2018 Category: Consumer Health News Tags: Nephrology Viewpoint Source Type: news
FDA Accepts Veloxis's Supplemental New Drug Application for the De Novo Indication for ENVARSUS XR(R)
COPENHAGEN, Denmark, April 20, 2018 -- (Healthcare Sales & Marketing Network) -- Veloxis Pharmaceuticals A/S announced today that the U.S. Food & Drug Administration (FDA) has accepted for standard review the Company's supplemental New Drug Application (s... Biopharmaceuticals, FDA Veloxis Pharmaceuticals, ENVARSUS, tacrolimus, kidney transplant (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 20, 2018 Category: Pharmaceuticals Source Type: news
Drug Safety update: Oral tacrolimus products: reminder to prescribe and dispense by brand name only
The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update for oral tacrolimus products. Inadvertent switching between tacrolimus products has been associated with (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - November 24, 2017 Category: Drugs & Pharmacology Source Type: news
Astagraf XL (Tacrolimus Extended-release Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 8, 2016 Category: Drugs & Pharmacology Source Type: news
