A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation
Conditions: Kidney Transplantation Interventions: Biological: TCD601; Drug: Tacrolimus (TAC); Drug: Corticosteroids (CS); Drug: Mycophenolate Mofetil (MMF); Drug: ATG Sponsors: ITB-Med LLC Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials
Prevalence of CYP3A5 Polymorphisms in the Donors and ABCB1 Polymorphisms in the Recipients Undergoing Pediatric Liver Transplant and Their Influence on Tacrolimus Levels and Graft Function.
Conditions: Pediatric Liver Transplant Interventions: Other: No intervention Sponsors: Institute of Liver and Biliary Sciences, India Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials
Evaluation of the Benefits of Administering Immunosuppressive Drugs as Single Daily Doses Over the First Year After Liver Transplantation (EASY)
Conditions: Liver Transplantation; Immunosuppression Interventions: Drug: XR-tacrolimus QD + MMF BID; Drug: LCP-tacrolimus QD + MMF BID; Drug: LCP-tacrolimus QD + MMF QD Sponsors: University Hospital, Limoges Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
Tacrolimus Exposure in Kidney Transplantation
Conditions: Kidney Transplant Rejection Sponsors: Seoul National University Hospital; Astellas Pharma Inc Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 4, 2024 Category: Research Source Type: clinical trials
Evaluation of Safety & Efficacy for the Prevention of Ocular GVHD With Ophthalmic Tacrolimus vs Cyclosporine in Allo-HSCT
Conditions: Ocular Graft-versus-host Disease Interventions: Drug: Cyclosporine ophthalmic solution 0.1%; Drug: Tacrolimus ophthalmic ointment 0.03% Sponsors: Hospital Universitario Dr. Jose E. Gonzalez Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 4, 2024 Category: Research Source Type: clinical trials
High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly
Conditions: Splenomegaly; Myelofibrosis Interventions: Drug: Ruxolitinib; Procedure: Allogeneic Stem Cell Transplantation; Drug: Levetiracetam; Drug: Eltrombopag; Drug: Busulfan; Drug: Romiplostim; Drug: Fludarabine phosphate; Drug: Cyclophosphamide; Drug: Mesna; Drug: Tacrolimus Sponsors: M.D. Anderson Cancer Center; Incyte Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 3, 2024 Category: Research Source Type: clinical trials
Tacrolimus in CD3+ T Lymphocytes
Conditions: Immunosuppression Interventions: Procedure: Venipunctures Sponsors: Erasmus Medical Center Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2024 Category: Research Source Type: clinical trials
Tacrolimus and Personalized Therapy to Prevent Acute Rejection Episodes
Conditions: Heart Transplant Failure Interventions: Drug: Tacrolimus （FK506） Sponsors: Fondazione IRCCS Policlinico San Matteo di Pavia Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 29, 2024 Category: Research Source Type: clinical trials
Analysis of the Effect of Donor CYP3A5 Gene Polymorphism on Early Tacrolimus Concentration and Postoperative Acute Renal Injury After Liver Transplantation
Conditions: Complete and Accurate Statistical Data of 60 Patients; CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately; Postoperative Tacrolimus Concentrations Were Accurately Recorded in 60 Patients; According to the Diagnosis and Grading Criteria of Acute Kidney Injury, the Cases and Grading of Postoperative Acute Kidney Injury in 60 Patients Were Counted; Scientific and Rigorous Statistical Analysis of Data Interventions: Other: CYP3A5*1* 、CYP3A5*1*3; Other: CYP3A5*3*3 Sponsors: Ziqiang Li Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials
Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant
Conditions: GVHD,Acute; Acute Leukemia; Myelodysplastic Syndromes; Myeloproliferative Disorders Interventions: Drug: ATG Combined with Tacrolimus and Mini Methotrexate Sponsors: University of Alabama at Birmingham Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials
Viral Immunity in Solid Organ Transplant Recipients: Monitoring Of The Response To Hepatitis B Booster Vaccination
Conditions: HBV; Kidney Transplantation; Liver Transplantation Interventions: Drug: Tacrolimus; Drug: Belatacept Sponsors: University Hospital, Grenoble; National Agency for Research on AIDS and Viral Hepatitis (ANRS) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
Topical Tacrolimus for Breast Cancer-related Lymphedema
Conditions: Lymphedema Interventions: Drug: Tacrolimus; Drug: Placebo Sponsors: Odense University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2024 Category: Research Source Type: clinical trials
Screening for Subclinical Antibody Mediated Rejection and Efficacy of Belatacept in the Context of de Novo Donor Specific Antibody After Kidney Transplantation (BELA-M-R)
Conditions: Kidney Transplant Rejection Interventions: Drug: Conversion to Belatacep; Drug: Standard of care treatment (SOC regimen) with Tacrolimus Sponsors: University Hospital, Rouen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials
225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
Conditions: Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome Interventions: Biological: Actinium Ac 225-DOTA-Daratumumab; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Procedure: Computed Tomography; Biological: Daratumumab; Procedure: Echocardiography; Drug: Fludarabine; Procedure: Hematopoietic Cell Transplantation; Biological: Indium In 111-DOTA-Daratumumab; Drug: Melphalan; Procedure: Multigated Acquisition Scan; Procedure: Radionuclide Imaging; Procedure: Single Photon Emission Computed Tomography; Drug: Sirolimus; Drug: Tacrolimus; R...
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials
Expanding Liver Transplant Immunosuppression Minimization Via Everolimus
Conditions: Liver Transplant Interventions: Drug: Everolimus; Drug: Tacrolimus (continued reduction); Drug: Tacrolimus (maintain 50% reduction); Drug: Everolimus Sponsors: National Institute of Allergy and Infectious Diseases (NIAID) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
