Fight Aging! Newsletter, December 25th 2023
This study generates a comprehensive single-cell transcriptomic atlas of human atherosclerosis including 118,578 high-quality cells from atherosclerotic coronary and carotid arteries. By performing systematic benchmarking of integration methods, we mitigated data overcorrection while separating major cell lineages. Notably, we define cell subtypes that have not been previously identified from individual human atherosclerosis scRNA-seq studies.
Besides characterizing granular cell-type diversity and communication, we leverage this atlas to provide insights into smooth muscle cell (SMC) modulation. We integrate genome...
Source: Fight Aging! - December 24, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Growing Thyroid Tissue in the Spleen to Restore Function
Over the past decade or so, researchers have demonstrated that it is possible to use existing organs as bioreactors to host organoids derived from other organ tissues. Functional liver tissue can be grown in lymph nodes, as can thymus tissue. Here, researchers show that thyroid organoids can be grown in the spleen. This is intended to help patients who have undergone thyroidectomy, but will this capability also be useful in the context of the aging of the thyroid gland? Interestingly, the aging of the thyroid is poorly understood in comparison to the interaction of aging with larger organs such as liver, kidney, or heart. ...
Source: Fight Aging! - December 19, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Unconscious + STEMI criteria: activate the cath lab?
Case submitted and written by Dr. Mazen El-Baba and Dr. Evelyn Dell, with edits from Jesse McLarenEMS brought a John Doe, in his 30s, who was found in an urban forest near a homeless encampment on a cool fall day. There were no signs of trauma on scene or on the patient. EMS reported an initial GCS of 8 with pupils equal and reactive. The patient had a witnessed generalized tonic-clonic seizure leading to GCS 4.Vitals: HR 45; systolic BP was 110-120; irregular respiratory rate; oxygen saturation was normal; tympanic temperature 30; glucose was 6. In the resuscitation room, the patient had another seizure that stopped after...
Source: Dr. Smith's ECG Blog - January 21, 2023 Category: Cardiology Authors: Jesse McLaren Source Type: blogs
Sarah ’ s Wheat Belly health and life transformation
Sarah’s story reminds us how the simple matter of diet can shape our lives for decades, affecting energy, body weight, emotional health–just about every aspect of our physical and social lives before we finally stumble on the right answers. After many years of struggling with poor health, relying on prescription medications that never addressed underlying causes, it therefore came as a surprise to Sarah that she could indeed achieve magnificent health without the drugs by simply following the diet programmed into human genetic code and supplementing nutrients that are deficient in modern life.
...
Source: Wheat Belly Blog - January 28, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open grain-free Inflammation joint pain wheat belly Source Type: blogs
CBD and other medications: Proceed with caution
Products containing cannabidiol (CBD) seem to be all the rage these days, promising relief from a wide range of maladies, from insomnia and hot flashes to chronic pain and seizures. Some of these claims have merit to them, while some of them are just hype. But it won’t hurt to try, right? Well, not so fast. CBD is a biologically active compound, and as such, it may also have unintended consequences. These include known side effects of CBD, but also unintended interactions with supplements, herbal products, and over-the-counter (OTC) and prescription medications.
Doubling up on side effects
While generally considered safe...
Source: Harvard Health Blog - January 11, 2021 Category: Consumer Health News Authors: Katsiaryna Bykov, PharmD, ScD Tags: Drugs and Supplements Marijuana Medical Research Safety Source Type: blogs
Treating mild hypothyroidism: Benefits still uncertain
Your thyroid, a tiny, butterfly-shaped gland located in front of your windpipe (trachea) and below your voice box (larynx) can have a profound impact on your health and well-being. Throughout life, your thyroid is constantly producing hormones that influence your metabolism. These hormones affect your mood, energy, body temperature, weight, heart, and more.
A brief overview of hypothyroidism
Your thyroid produces two kinds of thyroid hormones: T4, or thyroxine, and T3, or triiodothyronine. These hormones influence every cell, tissue, and organ in your body, from your muscles, bones, and skin to your digestive tract, brain,...
Source: Harvard Health Blog - September 28, 2020 Category: Consumer Health News Authors: Jeffrey Garber, MD, FACP, MACE Tags: Drugs and Supplements Heart Health Thyroid Disorders Source Type: blogs
You ’ re not still taking levothyroxine, are you?
The post You’re not still taking levothyroxine, are you? appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - October 23, 2019 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle autoimmune hashimoto's Thyroid undoctored Source Type: blogs
The Informed Thyroid: Address Your T3
It’s a peculiar, though not entirely unexpected phenomenon: You’d expect endocrinologists, specialists in glandular health, to be the champions of restoring optimal thyroid status. Instead, they are the most misinformed and neglectful.
Much of this is due to their ignorance of the emerging science that has emerged over the past two decades on the impact of INDUSTRIAL CHEMICALS on thyroid status, something they would not be aware of unless they examine the TOXICOLOGICAL evidence demonstrating that the thyroid gland and thyroid hormones are disrupted by common chemical exposures.
Ignore your ignorant endocrinolo...
Source: Wheat Belly Blog - March 23, 2019 Category: Cardiology Authors: Dr. Davis Tags: Hypothyroidism T3 thyroid hormone diy health free t3 undoctored wheat belly Source Type: blogs
Why Your Doctor Won ’ t Prescribe the T3 Thyroid Hormone
There is a simple reason why doctors typically refuse to prescribe the T3 thyroid hormone and it has nothing to do with science, side-effects, or potential dangers.
As with so many things in healthcare, it boils down to Big Pharma and money. The solution is to find a better-informed doctor.
The post Why Your Doctor Won’t Prescribe the T3 Thyroid Hormone appeared first on Dr. William Davis. (Source: Wheat Belly Blog)
Source: Wheat Belly Blog - February 26, 2019 Category: Cardiology Authors: Dr. Davis Tags: News & Updates cold hands feet fatigue hypothyroidism levothyroxine Synthroid t3 t4 tired undoctored wheat belly Wheat Belly Total Health Source Type: blogs
Thyroid Tune-Up
I am re-posting a classic Wheat Belly Blog post from a few years ago. Despite all our discussions about thyroid issues, there continues to be an enormous information gap: undiagnosed hypothyroidism, gross mismanagement sufficient to impair weight loss and increase cardiovascular risk, dismissing the importance of iodine, and ignorance among healthcare providers. This Thyroid Tune-up is therefore an updated version of the previous post.
Imagine that all the cars in your neighborhood run poorly because nobody bothers to tune-up their autos. I show you how to tune the cars and, lo and behold, 80% of the cars now run great. B...
Source: Wheat Belly Blog - January 6, 2019 Category: Cardiology Authors: Dr. Davis Tags: News & Updates autoimmune gluten-free grain-free grains hypothyroid levothyroxine Synthroid Source Type: blogs
Antidepressant "Withdrawal": Why Aren't Psychiatrists Seeing this "Common" Problem?
Over onTheNew York Timeswebsite, there is an article titled, "Many People Taking Antidepressants Discover They Cannot Quit. " Benedict Carey and Robert Gebeloff write about how long-term use of antidepressants is increasing, and some people have difficulties coming off the medications with symptoms that constitute a discontinuation syndrome. I'll let you read the article rather than quote it, because there was a lot wrong with the piece. It doesn't feel like a new idea that there are people who have protracted and miserable discontinuation syndromes--distinct from a recurrence of symptoms-- after stopping ...
Source: Shrink Rap - April 11, 2018 Category: Psychiatry Authors: Unknown Source Type: blogs
Antidepressant " Withdrawal " : Why Aren't Psychiatrists Seeing this " Common " Problem?
Over onTheNew York Timeswebsite, there is an article titled, "Many People Taking Antidepressants Discover They Cannot Quit." Benedict Carey and Robert Gebeloff write about how long-term use of antidepressants is increasing, and some people have difficulties coming off the medications with symptoms that constitute a discontinuation syndrome. I ' ll let you read the article rather than quote it, because there was a lot wrong with the piece. It doesn ' t feel like a new idea that there are people who have protracted and miserable discontinuation syndromes--distinct from a recurrence of symptoms-- after stoppi...
Source: Shrink Rap - April 11, 2018 Category: Psychiatry Authors: Unknown Source Type: blogs
“ I can ’ t lose weight on levothyroxine ”
I hear this complaint every day, yet the solution is SO simple.
The Undoctored lifestyle is magnificently effective to achieve weight loss, prevent or reverse hundreds of health conditions, and to free you from prescription medications.
But many people who take levothyroxine (Synthroid), the T4 thyroid hormone, report NO weight loss on the program, along with persistent abnormal symptoms such as low energy, dry skin, and thinning hair, even depression. This is not due to the failure of the program, but is due to the lack of the T3 thyroid hormone, the truly active form of thyroid hormone.
Learn why addressing and correc...
Source: Wheat Belly Blog - August 25, 2017 Category: Cardiology Authors: Dr. Davis Tags: Undoctored Wheat Belly Lifestyle Armour can't lose weight gluten-free grain-free health naturethroid reverse t3 Thyroid Weight Loss wellness Wheat Belly Total Health Source Type: blogs
