The Use of AI to Safely Reduce the Workload in Breast Cancer Screening With Mammography in Region Östergötland
Conditions: Artificial Intelligence; Breast Diseases; Neoplasms; Breast Neoplasms Interventions: Device: AI cancer detection system Sponsors: Ostergotland County Council, Sweden Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 1, 2024 Category: Research Source Type: clinical trials

Direct letters to relatives at risk of hereditary cancer —study protocol for a multi-center randomized controlled trial of healthcare-assisted versus family-mediated risk disclosure at Swedish cancer genetics clinics (DIRECT-study)
In this study, we evaluate healthcare-assisted direct letters to relatives at risk of hereditary cancer syndromes in a randomized controlled trial.MethodsProbands are recruited from Swedish outpatient cancer genetics clinics to this two-arm randomized controlled trial. The study recruits probands with either a pathogenic variant in a cancer susceptibility gene (BRCA1,BRCA2,PALB2,MLH1,MSH2,MSH6,PMS2) or probands with familial breast and colorectal cancer based on clinical and pedigree criteria. In both arms, probands receive standard care, i.e., are encouraged and supported to pass on information to relatives. In the interv...
Source: Trials - December 17, 2023 Category: Research Source Type: clinical trials

Sentinel Lymph Node Localisation With an Ultra-low Dose of Magtrace in Breast Cancer Patients
Conditions: Breast Cancer; Sentinel Lymph Node Interventions: Drug: Superparamagnetic Iron Oxide; Device: Technetium99 Sponsors: Sahlgrenska University Hospital, Sweden Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials

Nurse-administered, Gut-directed Hypnotherapy for Patients With Irritable Bowel Syndrome (IBS).
Conditions: Irritable Bowel Syndrome Interventions: Behavioral: Gut-directed hypnotherapy Sponsors: Sahlgrenska University Hospital, Sweden Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2023 Category: Research Source Type: clinical trials

Effects of High-intensity Interval Training in Patients With Systemic Lupus Erythematosus
Conditions: Lupus Erythematosus, Systemic Interventions: Behavioral: HIIT combined with resistance training Sponsors: Karolinska Institutet; Swedish Rheumatism Association; Region Örebro County; County Council of Norrbotten, Sweden; Karolinska University Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2023 Category: Research Source Type: clinical trials

Infections and Latent Autoimmune Diabetes in Adults
Conditions: Latent Autoimmune Diabetes in Adults; Type 2 Diabetes Sponsors: Karolinska Institutet; The Swedish Research Council; Swedish Council for Working Life and Social Research; Novo Nordisk A/S Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2023 Category: Research Source Type: clinical trials

Challenges regarding informed consent in recruitment to clinical research: a qualitative study of clinical research nurses ’ experiences
ConclusionsIn conclusion, upholding ethical research standards requires recognising various factors affecting patient voluntariness. Researchers and CRNs should prioritise refining the informed consent process, overcoming participation challenges, and aligning scientific rigour with personalised care. Additionally, a concerted effort is vital to meet the diverse needs of patient populations, including equitable inclusion of individuals with language barriers or cognitive limitations in clinical studies. These findings have significant implications for enhancing the ethics of clinical research and advancing person-centred c...
Source: Trials - December 11, 2023 Category: Research Source Type: clinical trials

Can Digitally Delivered First-line Osteoarthritis Treatment Improve Equal Access to Care
Conditions: Health Services Accessibility; First-line Treatment; Osteoarthritis Interventions: Behavioral: Digitally delivered first-line treatment for osteoarthritis; Behavioral: Face-to-face first-line treatment for osteoarthritis Sponsors: Joint Academy; Lund University; The Swedish Osteoarthritis Registry Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials

Promoting Sleep to Alleviate Pain - Arthroplasty
Conditions: Osteoarthritis, Knee; Osteoarthritis, Hip; Insomnia; Surgery; Pain, Postoperative; Postoperative Complications Interventions: Behavioral: Cognitive behavioral therapy for insomnia (CBT-I); Behavioral: Sleep education therapy (SET) Sponsors: Uppsala University; Acta Anaesthesiologica Scandinavica Foundation / SSAI; Swedish Government (under the national and regional ALF agreements) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 24, 2023 Category: Research Source Type: clinical trials

Adaptive Training Recommendations for Improved Physical Performance
Conditions: Maximal Oxygen Consumption; Physical Performance Interventions: Procedure: Adaptive exercise training; Procedure: Static exercise training Sponsors: The Swedish School of Sport and Health Sciences; Silicon Valley Exercise Analytics (svexa) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials

Digestibility of Different Plant-based Proteins in Humans With Ileostomy
Conditions: Ileostomy - Stoma Interventions: Dietary Supplement: Oat Protein, low bioavailability; Dietary Supplement: Oat Protein, high bioavailability; Dietary Supplement: Pea Protein, low bioavailability; Dietary Supplement: Pea Protein, high bioavailability; Dietary Supplement: Protein-free meal Sponsors: Örebro University, Sweden Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 21, 2023 Category: Research Source Type: clinical trials

ReDirection - Self Help Program for Minor Attracted Individuals
Conditions: Child Abuse Sexual; Pedophilia Interventions: Behavioral: ReDirection Sponsors: Karolinska Institutet; Centre for Psychiatry Research, Region Stockholm, Sweden; Link öping University, Sweden; Universitat Jaume I, Spain; Protect Children Organisation, Finland; National Institute of Mental Health, Czech Republic; Academy of the Police Force, Bratislava, Slovakia; Universitätsklinikum Hamburg-Eppendorf Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 15, 2023 Category: Research Source Type: clinical trials

Mi Bridge - Motivational Interviewing to Facilitate Help-seeking Among Minor Attracted Individuals
Conditions: Child Sexual Abuse; Pedophilia Interventions: Behavioral: Behavioral: MiBridge Sponsors: Karolinska Institutet; Centre for Psychiatry Research, Region Stockholm, Sweden; Link öping University, Sweden; Universitat Jaume I, Spain; Protect Children Organisation, Finland; National Institute of Mental Health, Czech Republic; Academy of the Police Force, Bratislava, Slovakia; Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 15, 2023 Category: Research Source Type: clinical trials

Mood Awareness Psychotherapy Support - A Randomised Feasibility Trial
Conditions: Depression, Anxiety Interventions: Behavioral: Internet Based Psychodynamic Psychotherapy Sponsors: University College, London; Link öping University, Sweden Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 15, 2023 Category: Research Source Type: clinical trials

Mood Awareness Psychotherapy Support
Conditions: Depression, Anxiety Interventions: Behavioral: Internet Based Psychodynamic Psychotherapy Sponsors: University College, London; Link öping University, Sweden Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 15, 2023 Category: Research Source Type: clinical trials