Communication Bridge ™-2 (CB2): an NIH Stage 2 randomized control trial of a speech-language intervention for communication impairments in individuals with mild to moderate primary progressive aphasia
DiscussionThe CB2 trial will supply Level 2 evidence regarding the efficacy of the Communication Bridge ™ intervention delivered in a telehealth service delivery model for individuals with mild to moderate PPA. An important by-product of the CB2 trial is that these data can be used to evaluate the efficacy of speech-language interventions delivered in both trial arms for persons with PPA. The impact of these data should not be overlooked as they will yield important insights examining why interventions work and for whom, which will advance effectiveness trials for speech-language interventions in PPA.Trial RegistrationCl...
Source: Trials - June 13, 2022 Category: Research Source Type: clinical trials

Design of the PERSPECTIVE study: PERsonalized SPEeCh Therapy for actIVE conversation in Parkinson ’s disease (randomized controlled trial)
ConclusionsWe will investigate the effectiveness of speech therapy in PD. Particular strengths of our study include a randomized and single-blinded design, the personalized treatment approach, the inclusion of PD patients irrespective of disease stage or severity of the speech complaint, the long-term follow-up, the adequate power, and the use of a patient-relevant primary endpoint. This will allow us to draw firm conclusions about the effectiveness of personalized and remote speech therapy for PD patients in all disease stages.Trial registrationClinicalTrials.govNCT03963388. Registered on May 24, 2019 (Source: Trials)
Source: Trials - April 8, 2022 Category: Research Source Type: clinical trials

Effects of Neuronavigated Theta Burst Stimulation in Therapy of Post-stroke Aphasia
Conditions:   Stroke, Ischemic;   Aphasia Non Fluent Interventions:   Device: Noninvasive transcranial brain stimulation: excitatory iTBS;   Device: Noninvasive transcranial brain stimulation: inhibitory cTBS;   Behavioral: Individual speech-language therapy (SLT);   Device: Sham TBS simulating left hemispheric iTBS Sponsor:   Institute of Psychiatry and Neurology, Warsaw Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 31, 2022 Category: Research Source Type: clinical trials

Sophrology Treatment for Patients With Glial Tumours Requiring Speech Therapy
Condition:   Glial Tumor Interventions:   Behavioral: Sophrology;   Behavioral: Speech therapy Sponsor:   Institut Cancerologie de l'Ouest Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2022 Category: Research Source Type: clinical trials