Comparison of 8 weeks standard treatment (rifampicin plus clarithromycin) vs. 4 weeks standard plus amoxicillin/clavulanate treatment [RC8 vs. RCA4] to shorten Buruli ulcer disease therapy (the BLMs4BU trial): study protocol for a randomized controlled multi-centre trial in Benin
DiscussionIf successful, this study will create a new paradigm for BU treatment, which could inform World Health Organization policy and practice. A shortened, highly effective, all-oral regimen will improve care of BU patients and will lead to a decrease in hospitalization-related expenses and indirect and social costs and improve treatment adherence. This trial may also provide information on treatment shortening strategies for other mycobacterial infections (tuberculosis, leprosy, or non-tuberculous mycobacteria infections).Trial registrationClinicalTrials.govNCT05169554. Registered on 27 December 2021. (Source: Trials)
Source: Trials - July 8, 2022 Category: Research Source Type: clinical trials
Effectiveness and Tolerability of Fitostimoline Plus vs Connettivina Bio Plus in Skin Graft
Conditions: Wounds and Injuries; Skin Graft Scar; Skin Graft Complications Interventions: Device: Fitostimoline plus; Device: Connettivina bio plus Sponsor: Federico II University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 7, 2022 Category: Research Source Type: clinical trials
Management of Skin Graft Donor Site Wound in Aged Patient
Condition: Skin Regrafting; Donor Site of Skin Grafting; Vancouver Scar Scale Interventions: Procedure: skin graft; Procedure: no skin graft Sponsor: Taipei Medical University WanFang Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 12, 2022 Category: Research Source Type: clinical trials
