Some Ideas for Handling Treatment-Resistant Bipolar Disorder
Bipolar disorder is being better understood each day. There is also ongoing research into its treatment.
But successfully treating bipolar disorder can involve several medication trials, and it can take years to achieve remission. Even if remission is attained, recurrence is the rule — not the exception. It’s not uncommon for all first-line treatments to be exhausted.
People in this situation may be considered by mental health professionals to be treatment-resistant. Luckily, there are treatments that can be tried when first-line, and even second-line, treatments for bipolar disorder fail.
What is Treatment ...
Source: Psych Central - June 8, 2013 Category: Psychiatry Authors: Natasha Tracy Tags: Anticonvulsants Antidepressants Atypical Antipsychotics Bipolar Cognitive-Behavioral Disorders General Medications Mood Stabilizers Psychotherapy Treatment Abilify Aripiprazole Bipolar Disorder Clinicians Consensus Depakote Source Type: news
Three Canadian Companies Recall All Lots of QuetiapineThree Canadian Companies Recall All Lots of Quetiapine
Health Canada says concerns over potential contamination during the manufacturing process are behind the recall. News Alerts (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 21, 2013 Category: Consumer Health News Tags: Psychiatry News Alert Source Type: news
Accord Healthcare case successfully resolved
Accord Healthcare Ltd. has successfully resolved the case against AstraZeneca relating to the validity of the patent covering quetiapine ER (Seroquel®). (Source: Pharmacy Europe)
Source: Pharmacy Europe - May 13, 2013 Category: Drugs & Pharmacology Source Type: news
Metformin overdose and hypoglycemia
3 out of 5 stars
Metformin overdose-induced hypoglycemia in the absence of other antidiabetic drugs. Al-Abri SA et al. Clin Toxicol 2013 Apr 1 [Epub ahead of print]
Abstract
Hypoglycemia association with metformin overdose has been reported but is distinctly unusual. In cases published previously, it has not been clear if factors other than metformin toxicity — such as co-ingestion of other hypoglycemic agents or poor nutrition — have been present.
This case report describes a 15-year-old girl who ingested an estimated 75 g of metformin and 3 g of quetiapine (Seroquel). On arrival at hospital, her glucose level was n...
Source: The Poison Review - May 9, 2013 Category: Toxicology Authors: Leon Tags: Medical case report hypoglycemia metformin overdose quetiapine Source Type: news
Fulminant Hepatic Failure in Association With QuetiapineFulminant Hepatic Failure in Association With Quetiapine
This case highlights the importance of considering drug-induced hepatotoxicity in cases of fulminant hepatic failure. Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 26, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Study Looks at Metformin and Atypical Antipsychotics
It's well known that atypical antipsychotics (AAPs) such as Zyprexa and Seroquel cause weight gain. The prescribing information for all AAPs contains warnings that blood sugar should be monitored because this weight gain can be associated with diabetes, particularly in people with existing risk factors.
I had those risk factors - diabetes is prevalent in my family history. From various psychiatric medications, including Seroquel, I gained a total of 80 pounds (to 205 pounds) and weighed 190 when I became concerned about my blood sugar and contacted my doctor. Sure enough, I had developed diabetes. The doctor started me on...
Source: About.com Bipolar Disorder - April 22, 2013 Category: Psychiatry Source Type: news
When the First Treatment for Depression Doesn’t Work
When the first treatment you try for your depression doesn’t work, it can feel utterly painful. As it is, depression makes you feel hopeless and helpless. An ineffective intervention might feel like the final straw.
But it’s actually not uncommon for the first treatment to be unsuccessful. In fact, about 40 to 50 percent of people don’t respond to the first antidepressant they’re prescribed, according to Jonathan E. Alpert, M.D., Ph.D, the associate director of the Massachusetts General Hospital Depression Clinical and Research Program and co-founder and co-director of the Depression and Anxiety Group Practice.
Sti...
Source: Psych Central - April 20, 2013 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Depression Disorders General Medications Self-Help Treatment Antidepressant Bipolar Disorder Co Director Depression And Anxiety Depression Anxiety Depression Treatment Final Straw Group Practice Hyland Hypothyroidism Incorr Source Type: news
Quetiapine-Induced Sleep-Related Eating Disorder-Like BehaviorQuetiapine-Induced Sleep-Related Eating Disorder-Like Behavior
Involuntary eating while sleepwalking has been reported with many medications, but not previously with the antipsychotic quetiapine, as seen in these two patients. Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 5, 2013 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
Meta-Analysis: Adjunctive atypical antipsychotic treatment for major depressive disorder
Source: PLoS Medicine
Area: News
Atypical antipsychotic medications are widely prescribed for the adjunctive treatment of depression, yet little is known about their total risk-benefit profile. This meta-analysis reviewed the efficacy and safety profiles of aripiprazole, olanzapine/fluoxetine combination (OFC), quetiapine, and risperidone used for the adjunctive treatment of depression.
The study which included 14 randomised controlled trials found that:
. All four drugs had significant effects on remission, as follows: aripiprazole (odds ratio [OR], 2.01; 95% CI, 1.48-2.73), OFC (OR, 1.42; 95% ...
Source: NeLM - Mental Health - March 13, 2013 Category: Psychiatry Source Type: news
US Court of Appeals Affirms Decision Finding Seroquel XR Formulation Patent Valid and Infringed
Friday, 15 February 2013
AstraZeneca today announced that, on 14 February 2013, the
United States Court of Appeals for the Federal Circuit summarily
upheld a lower court ruling that had found the formulation patent
protecting SEROQUEL XR (quetiapine... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 15, 2013 Category: Pharmaceuticals Source Type: news
U.S. appeals court finds Astra's Seroquel XR patent infringed
(Reuters) - A U.S. appeals court on Thursday upheld a lower court ruling that found the formulation patent for AstraZeneca's anti-psychotic drug Seroquel XR was valid and had been infringed by Mylan Inc and other companies seeking to sell generic versions of the medicine. (Source: Reuters: Health)
Source: Reuters: Health - February 15, 2013 Category: Consumer Health News Tags: healthNews Source Type: news
US court support validity of AstraZeneca’s Seroquel XR
AstraZeneca has announced that the US Court of Appeals for the Federal Circuit has upheld a lower court ruling that found its blockbuster drug Seroquel XR was valid and had been infringed by companies seeking to sell generic versions of the medicine. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - February 15, 2013 Category: Pharmaceuticals Source Type: news
Information on Seroquel found in Nurofen packs
Responding to media reports that the antipsychotic drug Seroquel had been found in a small number of packs of the over the counter pain killer Nurofen Plus the Royal Pharmaceutical Society has advised that patients should remain vigilant and if they are concerned at all ask their pharmacist for a (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - August 25, 2011 Category: Drugs & Pharmacology Source Type: news
Seroquel found in Nurofen packs
Responding to media reports that the antipsychotic drug Seroquel had been found in a small number of packs of the over the counter pain killer Nurofen Plus the Royal Pharmaceutical Society has advised that patients should remain vigilant and if they are concerned at all ask their pharmacist for a (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - August 25, 2011 Category: Drugs & Pharmacology Source Type: news
