DIC in septic shock
I have seen a couple of patients recently with profound septic shock ; one from meningococcemia and one from E. coli sepsis, develop DIC and then lose all 4 extremities. I was thinking what would be options for combating the microvascular thrombosis ? Xigris used to be available 12 years back but was taken off the market because of disappointing data in the PROWESS trial. Was it because Xigris was being used too indiscriminately ? If it had been used solely for a particular subset of pts...
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Source: Student Doctor Network - October 10, 2023 Category: Universities & Medical Training Authors: CRRT Tags: Critical Care Source Type: forums
Re: Venous thromboembolism with use of hormonal contraception and non-steroidal anti-inflammatory drugs: nationwide cohort study
(Source: BMJ Comments)
Source: BMJ Comments - September 26, 2023 Category: General Medicine Source Type: forums
Re: Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital: systematic review and network meta-analysis
(Source: BMJ Comments)
Source: BMJ Comments - May 28, 2023 Category: General Medicine Source Type: forums
Re: Rivaroxaban treatment for six weeks versus three months in patients with symptomatic isolated distal deep vein thrombosis: randomised controlled trial
(Source: BMJ Comments)
Source: BMJ Comments - December 9, 2022 Category: General Medicine Source Type: forums
Re: Comparative risk of thrombosis with thrombocytopenia syndrome or thromboembolic events associated with different covid-19 vaccines: international network cohort study from five European countries and the US
(Source: BMJ Comments)
Source: BMJ Comments - December 1, 2022 Category: General Medicine Source Type: forums
Re: Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital: systematic review and network meta-analysis
(Source: BMJ Comments)
Source: BMJ Comments - August 30, 2022 Category: General Medicine Source Type: forums
Meningioma and the SSS
64 yo man history of psychiatric issues with increasing forgetfulness over the last year had an MRI that showed left parasag vertex extraaxial mass (picture attached). Was taken for surgery With path showing atypical meningioma, low Ki67 but high mitoses. Considered subtotal due to wrapping around and invasion of the sup sag sinus. Surgeon was worried about RT hastening CVST (cerebral venous sinus thrombosis) and wanted to know if we would recommend RT. Don’t see many of these, is concern...
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Source: Student Doctor Network - July 28, 2022 Category: Universities & Medical Training Authors: Haybrant Tags: Radiation Oncology Source Type: forums
Re: Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study
(Source: BMJ Comments)
Source: BMJ Comments - June 6, 2022 Category: General Medicine Source Type: forums
Re: Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance
(Source: BMJ Comments)
Source: BMJ Comments - October 15, 2021 Category: General Medicine Source Type: forums
Thrombosis and Thrombocytopenia Associated With Adenoviral Vector-Based Vaccines Was Documented in Animals Twenty Years Ago
(Source: BMJ Comments)
Source: BMJ Comments - October 4, 2021 Category: General Medicine Source Type: forums
Re: Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study
(Source: BMJ Comments)
Source: BMJ Comments - September 16, 2021 Category: General Medicine Source Type: forums
