Re: Efficacy and safety outcomes of oral anticoagulants and antiplatelet drugs in the secondary prevention of venous thromboembolism: systematic review and network meta-analysis
(Source: BMJ Comments)
Source: BMJ Comments - August 20, 2015 Category: Journals (General) Source Type: forums
Re: Efficacy and safety of novel oral anticoagulants for treatment of acute venous thromboembolism: direct and adjusted indirect meta-analysis of randomised controlled trials
(Source: BMJ Comments)
Source: BMJ Comments - July 25, 2015 Category: Journals (General) Source Type: forums
Re: Superficial thrombophlebitis (superficial venous thrombosis)
(Source: BMJ Comments)
Source: BMJ Comments - June 25, 2015 Category: Journals (General) Source Type: forums
Re: Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases
(Source: BMJ Comments)
Source: BMJ Comments - June 15, 2015 Category: Journals (General) Source Type: forums
Re: Fresh evidence confirms links between newer contraceptive pills and higher risk of venous thromboembolism
(Source: BMJ Comments)
Source: BMJ Comments - May 30, 2015 Category: Journals (General) Source Type: forums
Re: Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases
(Source: BMJ Comments)
Source: BMJ Comments - May 29, 2015 Category: Journals (General) Source Type: forums
Re: Fresh evidence confirms links between newer contraceptive pills and higher risk of venous thromboembolism
(Source: BMJ Comments)
Source: BMJ Comments - May 27, 2015 Category: Journals (General) Source Type: forums
An end to the routine use of manual thrombectomy in STEMI?
Earlier this month the results of long awaited TOTAL trial were presented at the ACC meeting and simultaneously published in NEJM. TOTAL is the largest randomised trial to date which investigated the routine upfront manual thrombectomy with PCI alone in STEMI. 10,732 patients with STEMI undergoing primary PCI were randomised. The primary outcome was a composite of death from cardiovascular causes, recurrent myocardial infarction, cardiogenic shock, or NYHA class IV heart failure within 180 days. The key safety outcome was stroke within 30 days. Manual aspiration thrombectomy was associated with lower rates of incomple...
Source: Doc2Doc BMJ Cardiology - March 26, 2015 Category: Cardiology Authors: Heart Matters Source Type: forums
What is the future of "Triple Therapy" after coronary stenting?
Identifying the optimal regimen for antiplatelet therapy in patients requiring long-term anticoagulation following coronary stenting is an area that has traditionally been understudied. Although all major guidelines recommend (limited) triple therapy in this situation, these recommendations are either result of expert consensus or are largely based on observational data.
The WOEST trial was an open-labelled randomised trial and compared dual therapy (a combination of clopidogrel and vitamin K antagonist) with triple therapy (Aspirin, clopidogrel and vitamin K antagonist) in patients undergoing coronary stent...
Source: Doc2Doc BMJ Cardiology - November 17, 2014 Category: Cardiology Authors: Heart Matters Source Type: forums
Would you ask for bivalirudin in the ambulance on the way to the catheter lab for PCI?
IfI had a heart attack I would have only the faintest idea what my options really were and what their relative harms and merits might be. Perhaps as I was sucking on my aspirin tablet, I might ask the paramedic to leave the blood pressure cuff inflated for about five minutes to achieve a bit of ischaemic preconditioning. I might call for a tot of cardioprotective brandy: they say it goes well with diamorphine. Has anyone done a trial of oral alcohol for acute MI? I suppose I would let the ambulance take me to the nearest catheter lab for PCI, although more than an hour might elapse before I even reached the hospital ...
Source: Doc2Doc BMJ Cardiology - December 11, 2013 Category: Cardiology Authors: Richard Lehman Source Type: forums
is warfarin heading for a comeback?
I was looking at the re-align study of anticoagulation in mechanical valves that compared warfarin with dabigatran. In this group dabigatran was associated with more bleeding and thrombosis complications. Is warfarin heading for a comeback?
http://www.nejm.org/doi/full/10.1056/NEJMoa1300615
sadian (Source: Doc2Doc BMJ Cardiology)
Source: Doc2Doc BMJ Cardiology - November 14, 2013 Category: Cardiology Authors: sadian Source Type: forums
Rivaroxaban Gains FDA Indications for Treating and Preventing DVT and PE
The FDA has expanded the indication for rivaroxaban (Xarelto, Johnson & Johnson) to include the treatment of deep-vein thrombosis (DVT) and pulmonary embolism (PE) and to reduce the risk for recurrent DVT and PE.
The oral anticoagulant is already approved to reduce postsurgical risk for DVT and PE after hip- and knee-replacement surgery and to reduce the risk for stroke in people with atrial fibrillation. The new indication was granted under the FDA’s priority review program.
“Xarelto is the first oral anti-clotting drug approved to treat and reduce the recurrence of blood clots since the approval of warfarin nea...
Source: CardiologyNetwork.com - October 13, 2013 Category: Cardiology Authors: Indian Diabetics Foundation Team Source Type: forums
Adult Cardiac Surgery
In our adult cardiac surgery unit, coronary by-pass procedures and surgeries, both classical and minimally invasive, to repair and replace valves and treat aortic aneurisms and rhythm irregularities are performed. In addition, hypertrophic cardiomyopathy, pulmonary thromboembolism (pulmonary thromboenatherectomy) and aortic diseases are areas in which are department specializes._______________Cardiac Doctor Turkey (Source: Doc2Doc BMJ Cardiology)
Source: Doc2Doc BMJ Cardiology - February 27, 2013 Category: Cardiology Authors: Gretchen Hill Source Type: forums
Are the new anticoagulants a double whammy?
I've been going through my mail this morning and there is an alert around one of the new anticoagulants and patients with mechanical heart valves. As far as I can see prescribing these to postop patients is a bit of a double whammy- more bleeding immediately and then more rebund thrombosis if doses are missed. Has anyone used the new drugs for post-op patients?sadian (Source: Doc2Doc BMJ Cardiology)
Source: Doc2Doc BMJ Cardiology - January 17, 2013 Category: Cardiology Authors: sadian Source Type: forums
