DIC in septic shock

I have seen a couple of patients recently with profound septic shock ; one from meningococcemia and one from E. coli sepsis, develop DIC and then lose all 4 extremities. I was thinking what would be options for combating the microvascular thrombosis ? Xigris used to be available 12 years back but was taken off the market because of disappointing data in the PROWESS trial. Was it because Xigris was being used too indiscriminately ? If it had been used solely for a particular subset of pts... Read more
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Critical Care Source Type: forums