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Total 29483 results found since Jan 2013.
Formulation and optimization of polymeric nanoparticles loaded with riolozatrione: a promising nanoformulation with potential antiherpetic activity
Acta Pharm. 2023 Sep 14;73(3):457-473. doi: 10.2478/acph-2023-0028. Print 2023 Sep 1.ABSTRACTRiolozatrione (RZ) is a diterpenoid compound isolated from a dichloromethane extract of the Jatropha dioica root. This compound has been shown to possess moderate antiherpetic activity in vitro. However, because of the poor solubility of this compound in aqueous vehicles, generating a stable formulation for potential use in the treatment of infection is challenging. The aim of this work was to optimize and physio-chemically characterize Eudragit® L100-55-based polymeric nanoparticles (NPs) loaded with RZ (NPR) for in vitro antiher...
Source: Herpes - September 14, 2023 Category: Infectious Diseases Authors: Guadalupe Y Sol ís-Cruz Roc ío Alvarez-Roman Ver ónica M Rivas-Galindo Sergio Arturo Galindo-Rodr íguez David A Silva-Mares Iv án A Marino-Martínez Magdalena Escobar-Saucedo Luis A P érez-López Source Type: research
Musculoskeletal injury in an Australian professional ballet company, 2018-2021: 953 medical-attention and 706 time-loss injuries over 4 years
CONCLUSIONS: Almost all dancers required medical-attention for at least one injury during the surveillance period. Approximately 74% of injuries resulted in time-loss. BSI and ankle synovitis/impingement were of high burden and a high proportion of BSI were recurrent.PMID:37707788 | DOI:10.2519/jospt.2023.11858
Source: Physical Therapy - September 14, 2023 Category: Physiotherapy Authors: Louise Drysdale Zara Gomes Liam Toohey Kate Pumpa Phil Newman Source Type: research
Formulation and optimization of polymeric nanoparticles loaded with riolozatrione: a promising nanoformulation with potential antiherpetic activity
Acta Pharm. 2023 Sep 14;73(3):457-473. doi: 10.2478/acph-2023-0028. Print 2023 Sep 1.ABSTRACTRiolozatrione (RZ) is a diterpenoid compound isolated from a dichloromethane extract of the Jatropha dioica root. This compound has been shown to possess moderate antiherpetic activity in vitro. However, because of the poor solubility of this compound in aqueous vehicles, generating a stable formulation for potential use in the treatment of infection is challenging. The aim of this work was to optimize and physio-chemically characterize Eudragit® L100-55-based polymeric nanoparticles (NPs) loaded with RZ (NPR) for in vitro antiher...
Source: Acta Pharmaceutica - September 14, 2023 Category: Drugs & Pharmacology Authors: Guadalupe Y Sol ís-Cruz Roc ío Alvarez-Roman Ver ónica M Rivas-Galindo Sergio Arturo Galindo-Rodr íguez David A Silva-Mares Iv án A Marino-Martínez Magdalena Escobar-Saucedo Luis A P érez-López Source Type: research
Musculoskeletal injury in an Australian professional ballet company, 2018-2021: 953 medical-attention and 706 time-loss injuries over 4 years
CONCLUSIONS: Almost all dancers required medical-attention for at least one injury during the surveillance period. Approximately 74% of injuries resulted in time-loss. BSI and ankle synovitis/impingement were of high burden and a high proportion of BSI were recurrent.PMID:37707788 | DOI:10.2519/jospt.2023.11858
Source: Health Physics - September 14, 2023 Category: Physics Authors: Louise Drysdale Zara Gomes Liam Toohey Kate Pumpa Phil Newman Source Type: research
Formulation and optimization of polymeric nanoparticles loaded with riolozatrione: a promising nanoformulation with potential antiherpetic activity
Acta Pharm. 2023 Sep 14;73(3):457-473. doi: 10.2478/acph-2023-0028. Print 2023 Sep 1.ABSTRACTRiolozatrione (RZ) is a diterpenoid compound isolated from a dichloromethane extract of the Jatropha dioica root. This compound has been shown to possess moderate antiherpetic activity in vitro. However, because of the poor solubility of this compound in aqueous vehicles, generating a stable formulation for potential use in the treatment of infection is challenging. The aim of this work was to optimize and physio-chemically characterize Eudragit® L100-55-based polymeric nanoparticles (NPs) loaded with RZ (NPR) for in vitro antiher...
Source: Acta Pharmaceutica - September 14, 2023 Category: Drugs & Pharmacology Authors: Guadalupe Y Sol ís-Cruz Roc ío Alvarez-Roman Ver ónica M Rivas-Galindo Sergio Arturo Galindo-Rodr íguez David A Silva-Mares Iv án A Marino-Martínez Magdalena Escobar-Saucedo Luis A P érez-López Source Type: research
Musculoskeletal injury in an Australian professional ballet company, 2018-2021: 953 medical-attention and 706 time-loss injuries over 4 years
CONCLUSIONS: Almost all dancers required medical-attention for at least one injury during the surveillance period. Approximately 74% of injuries resulted in time-loss. BSI and ankle synovitis/impingement were of high burden and a high proportion of BSI were recurrent.PMID:37707788 | DOI:10.2519/jospt.2023.11858
Source: Health Physics - September 14, 2023 Category: Physics Authors: Louise Drysdale Zara Gomes Liam Toohey Kate Pumpa Phil Newman Source Type: research
Electrical dry needling versus a non-invasive multicomponent intervention in the treatment of myofascial trigger points in patients with chronic low back pain: A randomised clinical trial
CONCLUSIONS: In comparison to a non-invasive multicomponent intervention, electrical dry needling has more positive effects on disability, pain intensity, kinesiophobia, and reducing patients' sensitivity to myofascial trigger points pressure, at post-treatment and at 2 months.CLINICAL TRIAL REGISTRATION NUMBER: NCT04804228. Registered on May 28th, 2021. Available at https://clinicaltrials.gov/ct2/show/NCT04804228.PMID:37700695 | DOI:10.1177/02692155231201589
Source: Clinical Rehabilitation - September 13, 2023 Category: Rehabilitation Authors: Inmaculada Carmen Lara-Palomo Eduardo Antequera-Soler Manuel Fern ández-Sánchez Adelaida Mar ía Castro-Sánchez H éctor García-López Source Type: research
Surgical treatment of kyphosis in children and adolescents
Oper Orthop Traumatol. 2023 Sep 13. doi: 10.1007/s00064-023-00828-4. Online ahead of print.ABSTRACTOBJECTIVE: Correction of a pathological kyphosis to restore a balanced, low-pain or pain-free and load-bearing spine.INDICATIONS: Pronounced sagittal imbalance, progressive kyphosis despite conservative therapy, and neurological deficits are indications for surgery. Further surgical indications are severe therapy-resistant complaints and/or psychologically burdening cosmetic impairment. The guidelines for surgical indications are kyphosis angles of 75-80° thoracic and 30-50° lumbar.CONTRAINDICATIONS: No specific, but genera...
Source: Operative Orthopadie und Traumatologie - September 13, 2023 Category: Orthopaedics Authors: C E Heyde N von der H öh A V ölker Source Type: research
Designing environments that contribute to a reduction in the progression of Parkinson's disease; a literature review
Health Place. 2023 Sep 11;83:103105. doi: 10.1016/j.healthplace.2023.103105. Online ahead of print.ABSTRACTParkinson's Disease (PD), a prevalent neurological disorder, causes physical difficulties like stiffness and impaired walking and affects patients' emotional well-being. Regular exercise and exposure to enriched environments are crucial to managing these symptoms. This review aims to extract evidence from studies regarding built environments' impact on reducing the progression of PD. Keywords from 2005 to 2022 were used in five databases, including PubMed, Clarivate Web of Science, UGA Library, and Google Scholar. Man...
Source: Health and Place - September 13, 2023 Category: Environmental Health Authors: Farnaz Hesam Shariati Ashley Steffens Sadaf Adhami Source Type: research
