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Specialty: Urology & Nephrology
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Total 98062 results found since Jan 2013.
Elevated tacrolimus levels among COVID-19 kidney transplant recipients are associated with worse disease severity and clinical outcomes
CONCLUSION: Elevated tacrolimus levels occur in many renal transplant recipients with moderate to severe COVID-19 and are associated with worse clinical outcomes. Close drug monitoring is crucial to avoid toxicities and minimize over-immunosuppression complications.PMID:37675489 | DOI:10.5414/CN111137
Source: Clinical Nephrology - September 7, 2023 Category: Urology & Nephrology Authors: Angelito Yango Bipin Bista Bernard Fischbach Shana Machado Alexandra Clark Sanna Khoja Nicole Dion Giovana Saracino Jessica Taylor Hoylan Fernandez Sathishkumar Seeliyur Duraiswamy Giuliano Testa Source Type: research
Effect of canagliflozin in non-diabetic obese patients with albuminuria: A randomized, double-blind, placebo-controlled trial
CONCLUSION: Canagliflozin 100 mg daily was well tolerated but did not significantly reduce UACR in non-diabetic obese patients with microalbuminuria. However, a significant temporary decline in eGFR might reflect a subtle reduction in glomerular hyperfiltration.PMID:37675488 | DOI:10.5414/CN111143
Source: Clinical Nephrology - September 7, 2023 Category: Urology & Nephrology Authors: Primploy Greeviroj Pongpratch Puapatanakul Jeerath Phannajit Kullaya Takkavatakarn Wonngarm Kittanamongkolchai Patchaya Boonchaya-Anant Pisut Katavetin Kearkiat Praditpornsilpa Somchai Eiam-Ong Paweena Susantitaphong Source Type: research
Why is chronic kidney disease progressive? Evolutionary adaptations and maladaptations
Am J Physiol Renal Physiol. 2023 Sep 7. doi: 10.1152/ajprenal.00134.2023. Online ahead of print.ABSTRACTDespite significant advances in renal physiology, the global prevalence of chronic kidney disease (CKD) continues to increase. The emergence of multicellular organisms gave rise to increasing complexity of life resulting in tradeoffs reflecting ancestral adaptations to changing environments. Three evolutionary traits shape CKD over the lifespan: 1) variation in nephron number at birth, 2) progressive nephron loss with aging, and 3) adaptive kidney growth in response to decreased nephron number. Although providing plastic...
Source: Am J Physiol Renal P... - September 7, 2023 Category: Urology & Nephrology Authors: Robert L Chevalier Source Type: research
Intracellular signaling pathways of muscarinic acetylcholine receptor-mediated detrusor muscle contractions
In conclusion, cholinergic detrusor contraction and RhoA activation are mediated by both M2 and M3 receptors. Furthermore, whereas both Gαi and Gαq/11 proteins mediate UBSM contraction, the activation at the RhoA-ROCK pathway appears to be linked specifically to Gαi. These findings may aid the identification of more specific therapeutic targets for bladder dysfunctions.PMID:37675459 | DOI:10.1152/ajprenal.00261.2022
Source: Am J Physiol Renal P... - September 7, 2023 Category: Urology & Nephrology Authors: Helga Balla Kinga Borsodi Petra Őrsy B éla Horváth P éter József Molnár Ádám Lénárt M ónika Kosztelnik Éva Ruisanchez J ürgen Wess Stefan Offermanns P éter Nyirády Zolt án Benyó Source Type: research
Elevated tacrolimus levels among COVID-19 kidney transplant recipients are associated with worse disease severity and clinical outcomes
CONCLUSION: Elevated tacrolimus levels occur in many renal transplant recipients with moderate to severe COVID-19 and are associated with worse clinical outcomes. Close drug monitoring is crucial to avoid toxicities and minimize over-immunosuppression complications.PMID:37675489 | DOI:10.5414/CN111137
Source: Clinical Nephrology - September 7, 2023 Category: Urology & Nephrology Authors: Angelito Yango Bipin Bista Bernard Fischbach Shana Machado Alexandra Clark Sanna Khoja Nicole Dion Giovana Saracino Jessica Taylor Hoylan Fernandez Sathishkumar Seeliyur Duraiswamy Giuliano Testa Source Type: research
Effect of canagliflozin in non-diabetic obese patients with albuminuria: A randomized, double-blind, placebo-controlled trial
CONCLUSION: Canagliflozin 100 mg daily was well tolerated but did not significantly reduce UACR in non-diabetic obese patients with microalbuminuria. However, a significant temporary decline in eGFR might reflect a subtle reduction in glomerular hyperfiltration.PMID:37675488 | DOI:10.5414/CN111143
Source: Clinical Nephrology - September 7, 2023 Category: Urology & Nephrology Authors: Primploy Greeviroj Pongpratch Puapatanakul Jeerath Phannajit Kullaya Takkavatakarn Wonngarm Kittanamongkolchai Patchaya Boonchaya-Anant Pisut Katavetin Kearkiat Praditpornsilpa Somchai Eiam-Ong Paweena Susantitaphong Source Type: research
Elevated tacrolimus levels among COVID-19 kidney transplant recipients are associated with worse disease severity and clinical outcomes
CONCLUSION: Elevated tacrolimus levels occur in many renal transplant recipients with moderate to severe COVID-19 and are associated with worse clinical outcomes. Close drug monitoring is crucial to avoid toxicities and minimize over-immunosuppression complications.PMID:37675489 | DOI:10.5414/CN111137
Source: Clinical Nephrology - September 7, 2023 Category: Urology & Nephrology Authors: Angelito Yango Bipin Bista Bernard Fischbach Shana Machado Alexandra Clark Sanna Khoja Nicole Dion Giovana Saracino Jessica Taylor Hoylan Fernandez Sathishkumar Seeliyur Duraiswamy Giuliano Testa Source Type: research
Effect of canagliflozin in non-diabetic obese patients with albuminuria: A randomized, double-blind, placebo-controlled trial
CONCLUSION: Canagliflozin 100 mg daily was well tolerated but did not significantly reduce UACR in non-diabetic obese patients with microalbuminuria. However, a significant temporary decline in eGFR might reflect a subtle reduction in glomerular hyperfiltration.PMID:37675488 | DOI:10.5414/CN111143
Source: Clinical Nephrology - September 7, 2023 Category: Urology & Nephrology Authors: Primploy Greeviroj Pongpratch Puapatanakul Jeerath Phannajit Kullaya Takkavatakarn Wonngarm Kittanamongkolchai Patchaya Boonchaya-Anant Pisut Katavetin Kearkiat Praditpornsilpa Somchai Eiam-Ong Paweena Susantitaphong Source Type: research
Elevated tacrolimus levels among COVID-19 kidney transplant recipients are associated with worse disease severity and clinical outcomes
CONCLUSION: Elevated tacrolimus levels occur in many renal transplant recipients with moderate to severe COVID-19 and are associated with worse clinical outcomes. Close drug monitoring is crucial to avoid toxicities and minimize over-immunosuppression complications.PMID:37675489 | DOI:10.5414/CN111137
Source: Clinical Nephrology - September 7, 2023 Category: Urology & Nephrology Authors: Angelito Yango Bipin Bista Bernard Fischbach Shana Machado Alexandra Clark Sanna Khoja Nicole Dion Giovana Saracino Jessica Taylor Hoylan Fernandez Sathishkumar Seeliyur Duraiswamy Giuliano Testa Source Type: research
Effect of canagliflozin in non-diabetic obese patients with albuminuria: A randomized, double-blind, placebo-controlled trial
CONCLUSION: Canagliflozin 100 mg daily was well tolerated but did not significantly reduce UACR in non-diabetic obese patients with microalbuminuria. However, a significant temporary decline in eGFR might reflect a subtle reduction in glomerular hyperfiltration.PMID:37675488 | DOI:10.5414/CN111143
Source: Clinical Nephrology - September 7, 2023 Category: Urology & Nephrology Authors: Primploy Greeviroj Pongpratch Puapatanakul Jeerath Phannajit Kullaya Takkavatakarn Wonngarm Kittanamongkolchai Patchaya Boonchaya-Anant Pisut Katavetin Kearkiat Praditpornsilpa Somchai Eiam-Ong Paweena Susantitaphong Source Type: research
A 4-variable model to predict cardio-kidney events and mortality in chronic kidney disease: The Chronic Renal Insufficiency Cohort (CRIC) Study
Conclusion The combination of NT-proBNP, hs-cTnT, albuminuria and eGFR in a single 4-variable model provides a unique individual prognostic assessment of multiple cardio-kidney outcomes in CKD.PMID:37673057 | DOI:10.1159/000533223
Source: American Journal of Nephrology - September 6, 2023 Category: Urology & Nephrology Authors: Lu ís Carlos Ferreira Mendonça Miguel Bigotte Vieira Jo ão Sérgio Neves Paulo Castro Chaves Joao Pedro Ferreira Source Type: research
A more comprehensive assessment of pre-, intra-, and postoperative patient- and surgery-specific parameters and prehabilitation is required to improve pre-, peri- and postoperative risk estimation to optimize patient management with reduction of morbidity after major urological surgery
Urol Oncol. 2023 Sep 4:S1078-1439(23)00287-9. doi: 10.1016/j.urolonc.2023.08.010. Online ahead of print.NO ABSTRACTPMID:37673760 | DOI:10.1016/j.urolonc.2023.08.010
Source: Urologic Oncology - September 6, 2023 Category: Urology & Nephrology Authors: Marc A Furrer Patrick Y Wuethrich Source Type: research
